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COMPLEMENT COMPONENT 2 DEFICIENCY

Known as: C2 DEFICIENCY, C2D 
Lack of production of functional C2 protein, due to a genetic defect. It is the most common genetic complement deficiency. Ten percent of C2… 
National Institutes of Health

Related topics

Related topics

9 relations
Autoimmune DiseasesAutosomal recessive inheritanceC2 geneComplement C2, human

Papers overview

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2011
2011
A CROSSED MOLECULAR BEAM, LOW-TEMPERATURE KINETICS, AND THEORETICAL INVESTIGATION OF THE REACTION OF THE CYANO RADICAL (CN) WITH 1,3-BUTADIENE (C4H6). A ROUTE TO COMPLEX NITROGEN-BEARING MOLECULES IN…
We present a joint crossed molecular beam and kinetics investigation combined with electronic structure and statistical… 
2007
2007
Differentiation of C2D Macrophage Cells after Adoptive Transfer
ABSTRACT C2D macrophage cells protect immunocompromised mice from experimentally induced pneumonias after intraperitoneal (i.p… 
1997
1997
Two parallel routes of the complement‐mediated antibody‐dependent enhancement of HIV‐1 infection
Objective: To study the mechanism of the complement‐mediated antibodydependent enhancement (C'‐ADE) of HIV infection which may… 
1995
1995
Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock.
MRL-lpr/lpr mice are defective in the fas Ag/APO-1 apoptosis gene (CD95). Using the hepatotoxin D-galactosamine (D-GalNH2), we… 
1987
1987
Subacute cutaneous lupus erythematosus in multiple members of a family with C2 deficiency.
Deficiency of the second component of complement (C2d) has been associated with systemic lupus erythematosus (LE)-like syndromes… 
Highly Cited
1986
Highly Cited
1986
Impaired humoral immune response in complement C3‐deficient guinea pigs: absence of secondary antibody response
A recently described egenetically controlled C3 deficiency (C3D) in guinea pigs (GP) provided a unique model for studying the… 
Highly Cited
1985
Highly Cited
1985
Influence of genetically inherited complement deficiencies on humoral immune response in guinea pigs.
To assess the role of complement in the induction of the humoral immune response, we studied the antibody response of guinea pigs… 
1977
1977
A simple one-step hemolytic assay for C2 with C2-deficient human serum.
A simple one-step procedure has been developed for the molecular titration of C2 by utilizing the ability of the test material to… 
Highly Cited
1975
Highly Cited
1975
Inherited C2 deficiency and systemic lupus erythematosus: studies on a family.
A patient is described in which an inherited defect in the synthesis of C2 complement component coexisted with the disease… 
Highly Cited
1964
Highly Cited
1964
Mass Spectrometric Study of Photoionization. I. Apparatus and Initial Observations on Acetylene, Acetylene-d2, Benzene, and Benzene-d6
A windowless vacuum ultraviolet monochromator and mass spectrometer are combined for the study of photoionization processes in… 
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