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Complement component C5

Known as: C5, Complement, Complement, C5, Complement C5 
C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT… 
National Institutes of Health

Related topics

Related topics

24 relations
C5 geneChemotaxisComplement ActivationComplement C5:MCnc:Pt:Ser/Plas:Qn

Narrower (3)

C5-peptideComplement component 5 deficiencycomplement C5b-7 complex

Broader (2)

Complement C5, PrecursorImmunologic Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A small-molecule inhibitor of C 5 complement protein
1Global Discovery Chemistry, Novartis Institutes of Biomedical Research, Cambridge, MA, USA. 2Chemical Biology and Therapeutics… 
2017
2017
Clinical and molecular characterization of Factor I and C5 complement deficiencies : from diagnosis to pupulation studies
The Complement System is a part of the humoral immune response that, among other functions, is responsible for the defense… 
2017
2017
An antibody to a novel epitope on mouse complement C5 β-chain potently neutralizes C5 cleavage
2013
2013
Polypeptides binding to human complement c5
The present invention The invention also relates to for use in therapy, for example, C5 binding polypeptide for use in the… 
2011
2011
Polypeptide that binds to a human complement component c5
The present disclosure, among others, C5-binding polypeptides, and the use of said polypeptide in a method for treating or… 
2010
2010
desArgAntibody Fused to C 5 a or C 5 a neu Incubation with an Anti-HER 2 / In vitro on neu HER 2 / Decreased Survival of Human Breast Cancer Cells Expressing
2006
2006
Use of an anti c5 complement antibody to treat patients with sickle cell disease
1994
1994
Isolation of neutralizing anti-C5a monoclonal antibodies from a filamentous phage monovalent Fab display library.
1981
1981
The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase.
The cleavage of human complement component C5 to fragment C5b by the alternative pathway C5 convertase was studied. The… 
1981
1981
[Effect of complement 5 activation on neutrophil properties and the pharmacological intervention in various observed phenomena in a hemodialysis model].