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Complement component C1s

Known as: Esterase, C 1, C1s Complement, Esterase, C1 
A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1… 
National Institutes of Health

Related topics

Related topics

12 relations
C1S geneComplement C1s:MCnc:Pt:Ser/Plas:QnComplement component C1rProcess of secretion

Broader (2)

Complement component C1Immunologic Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
CDCP 1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic form of breast cancer that lacks the estrogen… 
1998
1998
Molecular cloning of a cDNA encoding a serine protease homologous to complement C1s precursor from rat C6 glial cells and its expression during glial differentiation.
1990
1990
Limited proteolysis of beta 2-microglobulin at Lys-58 by complement component C1s.
We have now demonstrated that activated complement component C1s cleaves beta 2-microglobulin at the position identical to that… 
1990
1990
Proteolysis of the heavy chain of major histocompatibility complex class I antigens by complement component C1s.
Highly Cited
1987
Highly Cited
1987
Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence.
The complete amino acid sequence (673 residues plus 15 residues of leader sequence) of human complement component C1s has been… 
1987
1987
C1 dissociation. Spontaneous generation in human serum of a trimer complex containing C1 inactivator, activated C1r, and zymogen C1s.
Activation of the C1 complex in the presence of C1 inactivator (C1 IA) is known to result in the formation of tetramer C1 IA-C1r… 
Highly Cited
1986
Highly Cited
1986
Functional model of subcomponent C1 of human complement.
1986
1986
Human complement component C1s. Partial sequence determination of the heavy chain and identification of the peptide bond cleaved during activation.
Human C1s proenzyme (Mr 83 000) was isolated by a rapid two-stage method involving affinity chromatography of C1 on IgG-Sepharose… 
1983
1983
The serine proteinase chain of human complement component C1s. Cyanogen bromide cleavage and N-terminal sequences of the fragments.
Human complement component C1s was purified from fresh blood by conventional methods of precipitation and chromatography. The… 
1969
1969
Specific antisera to C1s: detection of different electrophoretic species of C1s.
We have recently developed specific antisera to a highly homogeneous form of active C1 esterase (C1̄s̄)2 from human sera, and… 
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