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Complement component C1s
Known as:
Esterase, C 1
, C1s Complement
, Esterase, C1
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A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1…
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National Institutes of Health
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Related topics
Related topics
12 relations
C1S gene
Complement C1s:MCnc:Pt:Ser/Plas:Qn
Complement component C1r
Process of secretion
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Broader (2)
Complement component C1
Immunologic Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
CDCP 1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer
H. Wright
,
J. Arulmoli
,
+4 authors
O. Razorenova
2016
Corpus ID: 32031082
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic form of breast cancer that lacks the estrogen…
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1998
1998
Molecular cloning of a cDNA encoding a serine protease homologous to complement C1s precursor from rat C6 glial cells and its expression during glial differentiation.
H. Sakai
,
S. Nakashima
,
S. Yoshimura
,
Y. Nishimura
,
N. Sakai
,
Y. Nozawa
Gene
1998
Corpus ID: 25356565
1990
1990
Limited proteolysis of beta 2-microglobulin at Lys-58 by complement component C1s.
M. Nissen
,
P. Roepstorff
,
L. Thim
,
B. Dunbar
,
J. Fothergill
European Journal of Biochemistry
1990
Corpus ID: 24355955
We have now demonstrated that activated complement component C1s cleaves beta 2-microglobulin at the position identical to that…
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1990
1990
Proteolysis of the heavy chain of major histocompatibility complex class I antigens by complement component C1s.
H. Eriksson
,
M. Nissen
Biochimica et Biophysica Acta
1990
Corpus ID: 42452940
Highly Cited
1987
Highly Cited
1987
Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence.
C. M. Mackinnon
,
P. Carter
,
S. Smyth
,
B. Dunbar
,
J. Fothergill
European Journal of Biochemistry
1987
Corpus ID: 23955492
The complete amino acid sequence (673 residues plus 15 residues of leader sequence) of human complement component C1s has been…
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1987
1987
C1 dissociation. Spontaneous generation in human serum of a trimer complex containing C1 inactivator, activated C1r, and zymogen C1s.
A. Laurell
,
U. Mårtensson
,
A. Sjöholm
Journal of Immunology
1987
Corpus ID: 37299892
Activation of the C1 complex in the presence of C1 inactivator (C1 IA) is known to result in the formation of tetramer C1 IA-C1r…
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Highly Cited
1986
Highly Cited
1986
Functional model of subcomponent C1 of human complement.
V. Weiss
,
C. Fauser
,
J. Engel
Journal of Molecular Biology
1986
Corpus ID: 24974415
1986
1986
Human complement component C1s. Partial sequence determination of the heavy chain and identification of the peptide bond cleaved during activation.
S. Spycher
,
H. Nick
,
E. Rickli
European Journal of Biochemistry
1986
Corpus ID: 11967745
Human C1s proenzyme (Mr 83 000) was isolated by a rapid two-stage method involving affinity chromatography of C1 on IgG-Sepharose…
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1983
1983
The serine proteinase chain of human complement component C1s. Cyanogen bromide cleavage and N-terminal sequences of the fragments.
P. Carter
,
B. Dunbar
,
J. Fothergill
Biochemical Journal
1983
Corpus ID: 19486745
Human complement component C1s was purified from fresh blood by conventional methods of precipitation and chromatography. The…
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1969
1969
Specific antisera to C1s: detection of different electrophoretic species of C1s.
K. Nagaki
,
R. Stroud
Journal of Immunology
1969
Corpus ID: 45650757
We have recently developed specific antisera to a highly homogeneous form of active C1 esterase (C1̄s̄)2 from human sera, and…
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