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Complement component C1

Known as: Complement C1, Complement C1 [Chemical/Ingredient], Complement Component 1 
The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of… 
National Institutes of Health

Related topics

Related topics

11 relations
C1RL geneC1S geneProcess of secretionagonists

Narrower (1)

Complement component C1s

Broader (1)

Immunologic Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A Monoallelic Deletion of the TcCRT Gene Increases the Attenuation of a Cultured Trypanosoma cruzi Strain, Protecting against an In Vivo Virulent Challenge
Trypanosoma cruzi calreticulin (TcCRT) is a virulence factor that binds complement C1, thus inhibiting the activation of the… 
2011
2011
Age-related alterations in retinal neurovascular and inflammatory transcripts
Purpose Vision loss is one of the most common complications of aging, even in individuals with no diagnosed ocular disease… 
2010
2010
SERPING1 polymorphisms in polypoidal choroidal vasculopathy
Purpose To investigate whether common genetic variants in the complement component 1 inhibitor gene (serpin peptidase inhibitor… 
2010
2010
Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus
Recent studies have tested genetic variation at the C1QA, C1QB and C1QC (complement component 1, q subcomponent, A chain… 
Highly Cited
2007
Highly Cited
2007
The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration
The complement (C) system plays an important role in myelin breakdown during Wallerian degeneration (WD). The pathway and… 
2007
2007
Decrease in CD93 (C1qRp) Expression in a Human Monocyte‐Like Cell Line (U937) Treated with Various Apoptosis‐Inducing Chemical Substances
Human CD93, a receptor for complement component 1, subcomponent q phagocytosis (C1qRp), has been shown to be selectively… 
2002
2002
Binding of Tamm‐Horsfall protein to complement 1q and complement 1, including influence of hydrogen‐ion concentration
The goal of this study was to further characterize the interaction between an abundant urinary glycoprotein, Tamm‐Horsfall… 
1986
1986
Activation of the first component of human complement, C1, by monoclonal antibodies directed against different domains of subcomponent C1q.
Two monoclonal antibodies directed against C1q, and their (Fab)2 and Fab fragments, were used to study the mechanism of C1… 
Review
1984
Review
1984
Activation of C1.
The first component of complement, C1, is a calcium-dependent complex of two loosely interacting subunits: C1q, responsible for… 
Highly Cited
1979
Highly Cited
1979
C1 inhibitor-dependent dissociation of human complement component C1 bound to immune complexes.
The interaction of C1 inhibitor with complement component C1 bound to immune complexes was examined by using 125I-labelled C1… 
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