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Complement component C1r

Known as: Component 1r, Complement, Complement, C1r, C1r Complement 
A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact complement C1 complex. When COMPLEMENT C1Q is bound to… 
National Institutes of Health

Related topics

Related topics

11 relations
C1R geneComplement C1r:MCnc:Pt:Ser/Plas:QnComplement component C1sProcess of secretion

Broader (1)

Immunologic Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Reply to Arlaud et al.: Structure of the C1 complex and the unbound C1r2s2 tetramer
Arlaud et al. (1) raised concerns regarding our small-angle X-ray scattering (SAXS) and EM models of the unbound C1r2s2 tetramer… 
Review
2001
Review
2001
Structure and function of complement activating enzyme complexes: C1 and MBL-MASPs.
The complement system is a major effector arm of the immune defense contributing to the destruction of invading pathogens. There… 
1997
1997
Functional expression of the NKB1 killer cell inhibitory receptors on a γδ CTL clone
The receptors for major histocompatibility complex (MHC) class I molecules on NK cells prevent NK cell-mediated cytolysis… 
1996
1996
Exon structure of the gene encoding the human mannose-binding protein-associated serine protease light chain: comparison with complement C1r and C1s genes.
Mannan or mannose-binding protein (MBP) requires a novel serine protease termed MBP-associated serine protease (MASP) for… 
1992
1992
A calcium-binding monoclonal antibody that recognizes a non-calcium-binding epitope in the short consensus repeat units (SCRs) of complement C1r.
1992
1992
Complement component C1r mediated cleavage of the heavy chain of the major histocompatibility class I antigens.
1990
1990
Trimer and tetramer complexes containing C1 esterase inhibitor, C1r and C1s, in serum and synovial fluid of patients with rheumatic disease.
1989
1989
Expression of hemolytically active human complement component C1r proenzyme in insect cells using a baculovirus vector.
The gene of human C1r has been expressed in a baculovirus-insect-cell system via the pAc373 transplacement vector. The full… 
Highly Cited
1986
Highly Cited
1986
Nucleotide sequence of the cDNA coding for human complement C1r.
C1r is a zymogen of a serine protease that is involved in the activation of the first component of the classical pathway of the… 
1982
1982
Fluid phase activation of proenzymic C1r purified by affinity chromatography.
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