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Complement component C1r
Known as:
Component 1r, Complement
, Complement, C1r
, C1r Complement
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A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact complement C1 complex. When COMPLEMENT C1Q is bound to…
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National Institutes of Health
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Related topics
Related topics
11 relations
C1R gene
Complement C1r:MCnc:Pt:Ser/Plas:Qn
Complement component C1s
Process of secretion
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Broader (1)
Immunologic Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Prohaptoglobin is proteolytically cleaved in the endoplasmic reticulum by the complement C1r-like protein.
K. Wicher
,
E. Fries
Proceedings of the National Academy of Sciences…
2004
Corpus ID: 19408886
Many secretory proteins are synthesized as proforms that become biologically active through a proteolytic cleavage in the trans…
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Review
2001
Review
2001
Structure and function of complement activating enzyme complexes: C1 and MBL-MASPs.
P. Gál
,
G. Ambrus
Current protein and peptide science
2001
Corpus ID: 22112783
The complement system is a major effector arm of the immune defense contributing to the destruction of invading pathogens. There…
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1997
1997
Probing the structure of C1 with an anti-C1s monoclonal antibody: the possible existence of two forms of C1 in solution.
Y. Tseng
,
M. Phillips
,
V. Schumaker
Molecular Immunology
1997
Corpus ID: 37518382
1997
1997
Functional expression of the NKB1 killer cell inhibitory receptors on a γδ CTL clone
H. Nakajima
,
Y. I. Moore
,
M. Takiguchi
Immunogenetics
1997
Corpus ID: 33230724
The receptors for major histocompatibility complex (MHC) class I molecules on NK cells prevent NK cell-mediated cytolysis…
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1996
1996
Exon structure of the gene encoding the human mannose-binding protein-associated serine protease light chain: comparison with complement C1r and C1s genes.
Y. Endo
,
T. Sato
,
M. Matsushita
,
T. Fujita
International Immunology
1996
Corpus ID: 39749308
Mannan or mannose-binding protein (MBP) requires a novel serine protease termed MBP-associated serine protease (MASP) for…
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1992
1992
A calcium-binding monoclonal antibody that recognizes a non-calcium-binding epitope in the short consensus repeat units (SCRs) of complement C1r.
S. Ward
,
K. Ingham
Molecular Immunology
1992
Corpus ID: 29796661
1990
1990
Trimer and tetramer complexes containing C1 esterase inhibitor, C1r and C1s, in serum and synovial fluid of patients with rheumatic disease.
A. Laurell
,
Ulla Mårtensson
,
A. G. Sjöholm
JIM - Journal of Immunological Methods
1990
Corpus ID: 24747962
1989
1989
Expression of hemolytically active human complement component C1r proenzyme in insect cells using a baculovirus vector.
P. Gál
,
M. Sárvári
,
K. Szilágyi
,
P. Závodszky
,
V. Schumaker
Complement and Inflammation
1989
Corpus ID: 19176555
The gene of human C1r has been expressed in a baculovirus-insect-cell system via the pAc373 transplacement vector. The full…
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Highly Cited
1986
Highly Cited
1986
Nucleotide sequence of the cDNA coding for human complement C1r.
S. P. Leytus
,
K. Kurachi
,
K. Sakariassen
,
E. Davie
Biochemistry
1986
Corpus ID: 29639583
C1r is a zymogen of a serine protease that is involved in the activation of the first component of the classical pathway of the…
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1982
1982
Fluid phase activation of proenzymic C1r purified by affinity chromatography.
C. Villiers
,
A. Duplaa
,
G. Arlaud
,
M. Colomb
Biochimica et Biophysica Acta
1982
Corpus ID: 23512326
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