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Complement C3b

Known as: Complement Component 3b, Complement C3b [Chemical/Ingredient], Component 3b, Complement 
The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE… Expand
National Institutes of Health

Related topics

Related topics

18 relations
C3 geneComplement 3b ReceptorComplement C3b-C4b receptor:EntNum:Pt:RBC:QnComplement C3b-C4b receptor:PrThr:Pt:RBC:Ord
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Broader (1)

Immunologic Factors

Narrower (4)

Inactivated C3bcomplement C3d,gcomplement C3ecomplement C3f

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The structure of complement C3b provides insights into complement activation and regulation
The human complement system is an important component of innate immunity. Complement-derived products mediate functions… Expand
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Highly Cited
2004
Highly Cited
2004
Cleavage of Complement C3b to iC3b on the Surface of Staphylococcus aureus Is Mediated by Serum Complement Factor I
ABSTRACT Complement-mediated opsonization of Staphylococcus aureus bearing the dominant capsule serotypes, serotypes 5 and 8… Expand
Highly Cited
1997
Highly Cited
1997
Depletion of reactive advanced glycation endproducts from diabetic uremic sera using a lysozyme-linked matrix.
Diabetic uremic sera contain excessive amounts of reactive advanced glycation endproducts (AGEs), which accelerate the… Expand
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Highly Cited
1996
Highly Cited
1996
Surface-bound heparin fails to reduce thrombin formation during clinical cardiopulmonary bypass.
The hypothesis that heparin-coated perfusion circuits reduce thrombin formation and activity; fibrinolysis; and platelet… Expand
Highly Cited
1995
Highly Cited
1995
Modulation of antigen processing and presentation by covalently linked complement C3b fragment.
Ligands such as complement fragments (C3, C4), IgG or alpha 2-macroglobulin, which bind antigen (Ag) before their uptake by… Expand
Highly Cited
1995
Highly Cited
1995
The cellular reactions to experimental intracerebral hemorrhage
The resolution of an intracerebral hemorrhage can be measured by the occurrence of hemosiderin. Extravasation of blood elicits a… Expand
Highly Cited
1991
Highly Cited
1991
Sites within the complement C3b/C4b receptor important for the specificity of ligand binding.
Cysteine-rich repeated units of 40-70 amino acids are building blocks of many mammalian proteins, including 12 proteins of the… Expand
1987
1987
Human complement C3b/C4b receptor (CR1) mRNA polymorphism that correlates with the CR1 allelic molecular weight polymorphism.
The human C3b/C4b receptor (CR1) is a Mr approximately equal to 200,000 single-chain integral membrane glycoprotein of human… Expand
Highly Cited
1986
Highly Cited
1986
Influence of glycosylation on allelic and cell-specific Mr variation, receptor processing, and ligand binding of the human complement C3b/C4b receptor.
The human complement C3b/C4b receptor (CR1), a single chain membrane glycoprotein of Mr approximately 200,000, has several cell… Expand
1983
1983
Low ionic strength or chemical cross-linking of monomeric C3b increases its binding affinity to the human complement C3b receptor.
Quantitative studies of the interaction between a fragment of the third component of complement (C3b) and its receptor on human… Expand
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