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Inactivated C3b

Known as: C3b, Inactivated, C3bi, iC3b 
National Institutes of Health

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Related topics

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Broader (1)

Complement C3b

Papers overview

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Highly Cited
2002
Highly Cited
2002
Opsonization of Apoptotic Cells by Autologous iC3b Facilitates Clearance by Immature Dendritic Cells, Down-regulates DR and CD86, and Up-regulates CC Chemokine Receptor 7
Immature dendritic cells (iDCs) do not mature after uptake of apoptotic cells and may play a role in the induction of peripheral… 
Highly Cited
2000
Highly Cited
2000
Involvement of the Arp2/3 complex in phagocytosis mediated by FcγR or CR3
hagocytosis, the process by which cells internalize particles larger than 0.5 μm in diameter, is central to immunity. Fc… 
Highly Cited
1996
Highly Cited
1996
Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion
Integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) mediates the transient adhesion of polymorphonuclear leukocytes (PMN) to… 
Highly Cited
1996
Highly Cited
1996
Enhancement of macrophage phagocytosis upon iC3b deposition on apoptotic cells
Highly Cited
1990
Highly Cited
1990
Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch.
Neutrophil elastase has been implicated as a factor that impairs local host defenses in chronic Pseudomonas aeruginosa (Pa) lung… 
Highly Cited
1989
Highly Cited
1989
CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide
Polymorphonuclear leukocytes (PMN) from three patients deficient in the CD18 family of receptors (LFA-1, CR3, and p150,95… 
Highly Cited
1988
Highly Cited
1988
Roles of CR3 and mannose receptors in the attachment and ingestion of Leishmania donovani by human mononuclear phagocytes
Leishmania donovani is an obligate intracellular parasite of mammalian macrophages. Two macrophage receptors, the mannose-fucose… 
Highly Cited
1987
Highly Cited
1987
Aggregation of complement receptors on human neutrophils in the absence of ligand
C3bi receptors (CR3) on human polymorphonuclear leukocytes (PMN) bind ligand-coated particles and promote their ingestion. The… 
Highly Cited
1985
Highly Cited
1985
The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes.
We examined the role of the macrophage receptor for C3bi, the CR3, in the phagocytosis of Leishmania major promastigotes and… 
Highly Cited
1982
Highly Cited
1982
Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes
Cells expressing a membrane C receptor (CR(3)) specific for C3b-inactivator- cleaved C3b (C3bi) were identified by rosette assay… 
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