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Complement C3 Nephritic Factor

Known as: Complement C3 Nephritic Factor [Chemical/Ingredient], C3 Nephritic Factor, C 3 Nephritic Factor 
An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

Complement Inactivating AgentsImmunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2018
Highly Cited
2018
C3 Glomerulopathy: Ten Years' Experience at Mayo Clinic
Review
2012
Review
2012
Complement Diagnostics: Concepts, Indications, and Practical Guidelines
Aberrations in the complement system have been shown to be direct or indirect pathophysiological mechanisms in a number of… 
Highly Cited
2006
Highly Cited
2006
Accelerated Macrophage Apoptosis Induces Autoantibody Formation and Organ Damage in Systemic Lupus Erythematosus1
Increased monocyte/macrophage (Mφ) apoptosis occurs in patients with systemic lupus erythematosus (SLE) and is mediated, at least… 
Highly Cited
2001
Highly Cited
2001
Complement analysis in children with idiopathic membranoproliferative glomerulonephritis: A long‐term follow‐up
Fifty children with idiopathic membranoproliferative glomerulonephritis (MPGN), aged 2–14 years at apparent onset, were monitored… 
Review
1997
Review
1997
C3 nephritic factor and mesangiocapillary glomerulonephritis
Abstract. The association of a C3 splitting activity, known as C3 nephritic factor (C3NeF), with mesangiocapillary… 
1990
1990
T cell receptor Vβ genes expressed by IgG anti‐DNA autoantibody‐inducing T cells in lupus nephritis: Forbidden receptors and double‐negative T cells
In the (SWR × NZB)F1 (SNF1) model of lupus nephritis, pathogenic variety of IgG anti‐DNA autoantibodies are induced by certain T… 
1989
1989
Effect of decay-accelerating factor on the assembly of the classical and alternative pathway C3 convertases in the presence of C4 or C3 nephritic factor.
Decay-accelerating factor (DAF) is a 70,000 MW membrane protein that regulates the complement system on the cell surface. In the… 
1983
1983
C3 nephritic factor and hypocomplementaemia in a clinically healthy individual.
Nephritic factor was detected in an individual whose serum showed a selective decrease in the third component of complement (C3… 
1977
1977
The incorporation of C3 nephritic factor (C3NeF) into a stabilized C3 convertase, C3bBb(C3NeF), and its release after decay of convertase function.
The stabilized fluid phase C3 convertase formed during the interaction of C3NeF, B, D̄, and C3 and isolated as a 10S complex by… 
1971
1971
Continuing C3 breakdown after bilateral nephrectomy in patients with membrano-proliferative glomerulonephritis.
Serum levels of complement components and of C3 nephritic factor (C3NeF) were measured serially in two patients with membrano… 
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