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Complement C3 Nephritic Factor

Known as: Complement C3 Nephritic Factor [Chemical/Ingredient], C3 Nephritic Factor, C 3 Nephritic Factor 
An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND AND OBJECTIVES The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the… Expand
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Highly Cited
2010
Highly Cited
2010
Dense deposit disease (DDD), also known as membranoproliferative glomerulonephritis type II, is a rare kidney disorder that is… Expand
Highly Cited
2008
Highly Cited
2008
We describe the clinical features of 28 patients with juvenile dermatomyositis (JDM) and 1 patient with adult-onset… Expand
Highly Cited
2006
Highly Cited
2006
Introduction: Abnormal control of the complement alternative pathway (CAP) (factor H, factor I and membrane cofactor protein (MCP… Expand
Highly Cited
2006
Highly Cited
2006
Increased monocyte/macrophage (Mφ) apoptosis occurs in patients with systemic lupus erythematosus (SLE) and is mediated, at least… Expand
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Review
1997
Review
1997
Abstract. The association of a C3 splitting activity, known as C3 nephritic factor (C3NeF), with mesangiocapillary… Expand
Highly Cited
1990
Highly Cited
1990
The IgG fraction of serum from patients with membranoproliferative glomerulonephritis (MPGN) types I and II or partial… Expand
1990
1990
C3 nephritic factor is an IgG autoantibody that causes complement activation by stabilizing the alternative pathway C3 convertase… Expand
Highly Cited
1977
Highly Cited
1977
Complement C3 nephritic factor (NeF) produces alternative pathway-meciated C3 cleavage by binding to and stabilizing the… Expand
Highly Cited
1976
Highly Cited
1976
C3 nephritic factor (C3NeF) defined by the capacity of nephritic serum and its fractions to initiate loss of the B antigen of C3… Expand