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Complement C3 Nephritic Factor

Known as: Complement C3 Nephritic Factor [Chemical/Ingredient], C3 Nephritic Factor, C 3 Nephritic Factor 
An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding… 
National Institutes of Health

Related topics

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9 relations

Broader (2)

Complement Inactivating AgentsImmunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2007
2007
Glomerular Regeneration Is Delayed in Nephritic α8-Integrin-Deficient Mice: Contribution of α8-Integrin to the Regulation of Mesangial Cell Apoptosis
Background/Aims: α8β1-Integrin is expressed in mesangial cells. In vitro studies suggest a role for α8-integrin in the regulation… 
1992
1992
On the origin of C3 nephritic factor (antibody to the alternative pathway C3 convertase): evidence for the Adam and Eve concept of autoantibody production.
1990
1990
T cell receptor Vβ genes expressed by IgG anti‐DNA autoantibody‐inducing T cells in lupus nephritis: Forbidden receptors and double‐negative T cells
In the (SWR × NZB)F1 (SNF1) model of lupus nephritis, pathogenic variety of IgG anti‐DNA autoantibodies are induced by certain T… 
1987
1987
C3 nephritic factor determination. A comparison between two methods.
1985
1985
Selective C3 deficiency due to C3 nephritic factor in an apparently healthy girl
SummaryRoutine laboratory investigations performed on the serum of an 8-year-old girl examined because of a moderate degree of… 
1984
1984
Protection of the classical and alternative complement pathway C3 convertases, stabilized by nephritic factors, from decay by the human C3b receptor
Formation and function of the classical (C4b, 2a) and alternative (C3b, Bb) complement pathway C3 convertases are regulated by… 
1983
1983
C3 nephritic factor and hypocomplementaemia in a clinically healthy individual.
Nephritic factor was detected in an individual whose serum showed a selective decrease in the third component of complement (C3… 
1980
1980
Activation of the classic complement pathway in patients with the C3 nephritic factor.
5 patients, including 4 with partial lipodystrophy and 1 with dense deposit disease (type II mesangiocapillary glomerulonephritis… 
1977
1977
Disorders of the complement system in lipodystrophy.
1976
1976
Serum factors activating the alternative complement pathway in autoimmune disease: description of two different factors from patients with systemic lupus erythematosus.
Serum factors which activated the alternative pathway of complement were detected in 10 of 26 patients with systemic lupus… 
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