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Complement C3 Nephritic Factor
Known as:
Complement C3 Nephritic Factor [Chemical/Ingredient]
, C3 Nephritic Factor
, C 3 Nephritic Factor
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An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (2)
Complement Inactivating Agents
Immunologic Factors
Process of secretion
agonists
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Eculizumab for dense deposit disease and C3 glomerulonephritis.
A. Bomback
,
Richard J. H. Smith
,
+9 authors
G. Appel
American Society of Nephrology. Clinical Journal
2012
Corpus ID: 22512020
BACKGROUND AND OBJECTIVES The principle defect in dense deposit disease and C3 glomerulonephritis is hyperactivity of the…
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Highly Cited
2010
Highly Cited
2010
Anti-factor B autoantibody in dense deposit disease.
S. Strobel
,
M. Zimmering
,
K. Papp
,
J. Prechl
,
M. Józsi
Molecular Immunology
2010
Corpus ID: 23762687
Highly Cited
2008
Highly Cited
2008
Predictors of Acquired Lipodystrophy in Juvenile-Onset Dermatomyositis and a Gradient of Severity
A. Bingham
,
Gulnara Mamyrova
,
+19 authors
L. Rider
Medicine
2008
Corpus ID: 324731
We describe the clinical features of 28 patients with juvenile dermatomyositis (JDM) and 1 patient with adult-onset…
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Highly Cited
2006
Highly Cited
2006
Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome
A. Servais
,
V. Frémeaux-Bacchi
,
+7 authors
F. Fakhouri
Journal of Medical Genetics
2006
Corpus ID: 32789571
Introduction: Abnormal control of the complement alternative pathway (CAP) (factor H, factor I and membrane cofactor protein (MCP…
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Highly Cited
2006
Highly Cited
2006
Accelerated Macrophage Apoptosis Induces Autoantibody Formation and Organ Damage in Systemic Lupus Erythematosus1
Michael F Denny
,
P. Chandaroy
,
+6 authors
M. Kaplan
Journal of Immunology
2006
Corpus ID: 24994830
Increased monocyte/macrophage (Mφ) apoptosis occurs in patients with systemic lupus erythematosus (SLE) and is mediated, at least…
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Highly Cited
2001
Highly Cited
2001
Complement analysis in children with idiopathic membranoproliferative glomerulonephritis: A long‐term follow‐up
R. Schwertz
,
U. Rother
,
Dietrich Anders
,
N. Gretz
,
K. Schärer
,
M. Kirschfink
Pediatric Allergy and Immunology
2001
Corpus ID: 25202053
Fifty children with idiopathic membranoproliferative glomerulonephritis (MPGN), aged 2–14 years at apparent onset, were monitored…
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Review
1997
Review
1997
C3 nephritic factor and mesangiocapillary glomerulonephritis
D. Williams
Pediatric nephrology (Berlin, West)
1997
Corpus ID: 20067881
Abstract. The association of a C3 splitting activity, known as C3 nephritic factor (C3NeF), with mesangiocapillary…
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Highly Cited
1994
Highly Cited
1994
Hypocomplementaemia of poststreptococcal acute glomerulonephritis is associated with C3 nephritic factor (C3NeF) IgG autoantibody activity.
V. Frémeaux-Bacchi
,
L. Weiss
,
C. Demouchy
,
A. May
,
S. Palomera
,
M. Kazatchkine
Nephrology, Dialysis and Transplantation
1994
Corpus ID: 23252299
We have observed that decreased plasma levels of C3 in the serum of three children with poststreptococcal acute…
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Highly Cited
1977
Highly Cited
1977
Heterogeneity of nephritic factor and its identification as an immunoglobulin.
A. Davis
,
J. Ziegler
,
E. Gelfand
,
F. Rosen
,
C. Alper
Proceedings of the National Academy of Sciences…
1977
Corpus ID: 20215767
Complement C3 nephritic factor (NeF) produces alternative pathway-meciated C3 cleavage by binding to and stabilizing the…
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Highly Cited
1976
Highly Cited
1976
C3 nephritic factor (C3NeF): stabilization of fluid phase and cell-bound alternative pathway convertase.
M. Daha
,
D. Fearon
,
K. Austen
Journal of Immunology
1976
Corpus ID: 46720327
C3 nephritic factor (C3NeF) defined by the capacity of nephritic serum and its fractions to initiate loss of the B antigen of C3…
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