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Complement C1q Subcomponent Subunit A

Known as: Complement Component 1, q Subcomponent, Alpha Polypeptide, Complement Component C1q, A Chain, C1QA 
Complement C1q subcomponent subunit A (245 aa, ~26 kDa) is encoded by the human C1QA gene. This protein plays a role in the activation of the… 
National Institutes of Health

Related topics

Related topics

7 relations
C1QA geneC1QA wt AlleleComplement ActivationComplement Pathway, Classical

Papers overview

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2017
2017
Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain
The complement cascade not only provides protection from infection but can also mediate destructive inflammation. Complement is… 
Highly Cited
2016
Highly Cited
2016
C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury
C1q represents the initiating protein of the classical complement cascade, however recent findings indicate pathway independent… 
2016
2016
COMPLEMENT C 1 Q HAS A NOVEL TETRAMERIC STRUCTURE IN NILE TILAPIA ( OREOCHROMIS NILOTICUS )
Complement C1q is the first subcomponent of the classical complement pathway, and a major molecule connecting link between innate… 
2014
2014
Amyloid beta (A4) precursor protein expression in human periodontitis-affected gingival tissues.
Highly Cited
1999
Highly Cited
1999
C1q binding to liposomes is surface charge dependent and is inhibited by peptides consisting of residues 14-26 of the human C1qA chain in a sequence independent manner.
1998
1998
Characterization of transcript processing of the gene encoding precerebellin-1.
1994
1994
Substrate specificities of murine C1s.
An early step in the initiation of the classical C pathway is the proteolytic activation of component C4 by subcomponent C1-s. We… 
1989
1989
The quaternary structure in solution of human complement subcomponent C1r2C1s2.
C1r2C1s2 is a subcomponent of first component C1 of the complement cascade. Previously two distinct models for its structure have… 
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