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Codon Genus

Known as: Codon 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff
We describe a new computer program, SnpEff, for rapidly categorizing the effects of variants in genome sequences. Once a genome… Expand
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Highly Cited
2007
Highly Cited
2007
STAT3 mutations in the hyper-IgE syndrome.
BACKGROUND The hyper-IgE syndrome (or Job's syndrome) is a rare disorder of immunity and connective tissue characterized by… Expand
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Review
2004
Review
2004
Codon bias and heterologous protein expression.
The expression of functional proteins in heterologous hosts is a cornerstone of modern biotechnology. Unfortunately, proteins are… Expand
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Highly Cited
2003
Highly Cited
2003
Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor.
Although changes in nucleotide sequence affecting the composition and the structure of proteins are well known, functional… Expand
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Highly Cited
2001
Highly Cited
2001
Recognition of Cognate Transfer RNA by the 30S Ribosomal Subunit
Crystal structures of the 30S ribosomal subunit in complex with messenger RNA and cognate transfer RNA in the A site, both in the… Expand
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Highly Cited
2000
Highly Cited
2000
Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology.
Proteome analysis is most commonly accomplished by a combination of two-dimensional gel electrophoresis (2DE) to separate and… Expand
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Highly Cited
1999
Highly Cited
1999
Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis.
We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917 genes, respectively, from Caenorhabditis… Expand
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Highly Cited
1997
Highly Cited
1997
Congenital leptin deficiency is associated with severe early-onset obesity in humans
The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene encoding leptin, an adipocyte-specific… Expand
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Highly Cited
1994
Highly Cited
1994
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast and ovarian cancer, has been… Expand
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Highly Cited
1990
Highly Cited
1990
The 'effective number of codons' used in a gene.
A simple measure is presented that quantifies how far the codon usage of a gene departs from equal usage of synonymous codons… Expand
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