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Clonidine

Known as: Clonidinum, 2-[(2,6-Dichlorophenyl)imino]imidazoline, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- 
An imidazoline derivate and centrally-acting alpha-adrenergic agonist, with antihypertensive activity. Clonidine binds to and stimulates central… 
National Institutes of Health

Related topics

Related topics

42 relations
168 HR Clonidine 0.00833 MG/HR Transdermal SystemAlcohol-Induced Disorders, Nervous SystemAttention deficit hyperactivity disorderClonidine Hydrochloride

Narrower (16)

4-azidoclonidineCBS 1276CatapresChlofazoline

Broader (5)

Adrenergic alpha-2 Receptor AgonistsAntihypertensive AgentsCentral Nervous System StimulantsImidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Reduced growth hormone (GH) responsiveness to combined GH‐releasing hormone and pyridostigmine administration in the Prader–Willi syndrome
It is unclear whether the blunted GH secretion in Prader–Willi Syndrome (PWS) is a true deficiency, or merely secondary to… 
1998
1998
The Effect of Clonidine or Midazolam Premedication on Perioperative Responses During Ketamine Anesthesia
The use of ketamine as a sole anesthetic induces marked central sympathetic stimulation, causing increased heart rate, blood… 
1986
1986
Clonidine suppression test for pheochromocytoma: examples of misleading results.
Baseline plasma norepinephrine (NE) and epinephrine (E) levels over 2000 pg/ml or failure to suppress to less than 500 pg/ml… 
Highly Cited
1982
Highly Cited
1982
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Prolonged treatment of spontaneously hypertensive (SHR) rats with either methyldopa or clonidine significantly and similarly… 
1982
1982
Outpatient opiate detoxification with clonidine.
The finding that clonidine has significant withdrawal-suppressing effects in opiate addicts has led to clinical testing of its… 
1981
1981
Sedative and cardiovascular effects of clonidine and nitrazepam.
Five healthy male subjects, aged 26 to 35 yr, received single oral doses of clonidine 0.3 mg, nitrazepam 20 mg, or placebo double… 
Highly Cited
1979
Highly Cited
1979
Interaction of antidepressants with clonidine on rat brain total 3-methoxy-4-hydroxyphenylglycol.
The effects of some antidepressants on brain total 3-methoxy-4-hydroxyphenylglycol (MHPG) were studied in the rat. Desipramine… 
1979
1979
Antihypertensive effects of clonidine in tetraplegic subjects devoid of central sympathetic control.
1. The effects of 300 microgram of oral clonidine on blood pressure, heart rate, plasma noradrenaline and adrenaline… 
1975
1975
Clonidine in menopausal flushing: a double-blind trial.
Twelve hypertensive women were treated with low doses of the antihypertensive drug clonidine for their menopausal flushing in a… 
1971
1971
Effects of clonidin and chlorthalidone on blood pressure and glucose tolerance in hypertensive patients.