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Clonidine

Known as: Clonidinum, 2-[(2,6-Dichlorophenyl)imino]imidazoline, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- 
An imidazoline derivate and centrally-acting alpha-adrenergic agonist, with antihypertensive activity. Clonidine binds to and stimulates central… 
National Institutes of Health

Related topics

Related topics

42 relations
168 HR Clonidine 0.00833 MG/HR Transdermal SystemAlcohol-Induced Disorders, Nervous SystemAttention deficit hyperactivity disorderClonidine Hydrochloride

Narrower (16)

4-azidoclonidineCBS 1276CatapresChlofazoline

Broader (5)

Adrenergic alpha-2 Receptor AgonistsAntihypertensive AgentsCentral Nervous System StimulantsImidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Intrathecal clonidine alleviates allodynia in neuropathic rats: interaction with spinal muscarinic and nicotinic receptors.
BACKGROUND Intrathecally administered clonidine increases release of spinal acetylcholine, which may be related to its analgesic… 
Highly Cited
1990
Highly Cited
1990
Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems
Highly Cited
1983
Highly Cited
1983
Catecholamine metabolism in the rat locus coeruleus as studied by in vivo differential pulse voltammetry. II. Pharmacological and behavioral study
Review
1983
Review
1983
Minireview. Catecholamines and the sleep-wake cycle. II. REM sleep.
Highly Cited
1982
Highly Cited
1982
Adrenergic receptor sensitivity in depression. Effects of clonidine in depressed patients and healthy subjects.
Several recent investigations have raised the possibility that the sensitivity of alpha 2-adrenergic receptor may be of etiologic… 
Highly Cited
1981
Highly Cited
1981
Growth Hormone and other Responses to Clonidine in Patients with Endogenous Depression
Summary The growth hormone response to clonidine was significantly less in 10 drug-free patients with endogenous depression than… 
Highly Cited
1974
Highly Cited
1974
Antinociceptive effects of some α-sympathomimetic agents
Highly Cited
1973
Highly Cited
1973
Localization of the central cardiovascular action of clonidine
1 The fall in arterial blood pressure with bradycardia that occurs on injection of clonidine into the cerebral ventricles and… 
Highly Cited
1972
Highly Cited
1972
Hypothermic effect of alpha-sympathomimetic agents and their antagonism by adrenergic and cholinergic blocking drugs.
Highly Cited
1970
Highly Cited
1970
Studies on the action of some psychoactive drugs on central noradrenaline neurons after inhibition of dopamine-beta-hydroxylase.
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