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Clonidine

Known as: Clonidinum, 2-[(2,6-Dichlorophenyl)imino]imidazoline, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- 
An imidazoline derivate and centrally-acting alpha-adrenergic agonist, with antihypertensive activity. Clonidine binds to and stimulates central… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Objective To systematically evaluate the efficacy of treatments for tics and the risks associated with their use. Methods This… Expand
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Review
2018
Review
2018
Abstract To date, no medication is proven to be effective in treating core symptoms of autism spectrum disorder (ASD… Expand
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Review
2006
Review
2006
  • M. Rosner, M. Okusa
  • Clinical journal of the American Society of…
  • 2006
  • Corpus ID: 11711162
Acute renal failure (ARF) occurs in up to 30% of patients who undergo cardiac surgery, with dialysis being required in… Expand
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Highly Cited
2006
Highly Cited
2006
Background:  The purpose of this study was to compare the onset and duration of sensory and motor block, as well as the… Expand
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Highly Cited
1994
Highly Cited
1994
Clonidine, an antihypertensive drug, binds to alpha 2-adrenergic and imidazoline receptors. The endogenous ligand for imidazoline… Expand
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Highly Cited
1984
Highly Cited
1984
We have studied the responses to electrical and chemical stimulation of the ventrolateral medulla in the chloralose-anesthetized… Expand
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Highly Cited
1978
Highly Cited
1978
In a double-blind, placebo-controlled, cross-over trial, clonidine eliminated objective signs and subjective symptoms of opiate… Expand
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Highly Cited
1978
Highly Cited
1978
NORADRENERGIC neurones of the locus coeruleus (LC; A6 of ref. 1) are inhibited by the systemic or local administration of… Expand
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Highly Cited
1975
Highly Cited
1975
By means of single unit recording techniques it was found that a small systemically administered (intravenous) dose of the alpha… Expand
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Highly Cited
1970
Highly Cited
1970
Abstract Clonidine increased the flexor reflex of spinal rats also after depletion of all known noradrenaline stores, indicating… Expand
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