Clonidine

Known as: Clonidinum, 2-[(2,6-Dichlorophenyl)imino]imidazoline, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- 
An imidazoline derivate and centrally-acting alpha-adrenergic agonist, with antihypertensive activity. Clonidine binds to and stimulates central… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
BACKGROUND Caudal block is a common technique for paediatric analgesia but with the disadvantage of short duration of action… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 4
Is this relevant?
Review
2009
Review
2009
The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. The authors searched for… (More)
  • figure 1
  • table 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND Perioperative myocardial ischemia occurs in 20-40% of patients at risk for cardiac morbidity and is associated with a… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Experimental studies and clinical observations suggest a possible role for opioids to induce pain and hyperalgesia on… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
We examined whether the known noradrenergic attenuation of the alerting effect (the beneficial effect of a warning cue) results… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Department of Anesthesia, Wake Forest Uniuersity Medical Center, Winston-Salem, NC 27157-1009 (USA), b Pare Consultation Sercice… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Patients with reflex sympathetic dystrophy or causalgia characteristically have ongoing pain and pain to light touch… (More)
Is this relevant?
Highly Cited
1978
Highly Cited
1978
In a double-blind, placebo-controlled, cross-over trial, clonidine eliminated objective signs and subjective symptoms of opiate… (More)
Is this relevant?
Highly Cited
1978
Highly Cited
1978
NORADRENERGIC neurones of the locus coeruleus (LC; A6 of ref. 1) are inhibited by the systemic or local administration of… (More)
Is this relevant?
Highly Cited
1975
Highly Cited
1975
By means of single unit recording techniques it was found that a small systemically administered (intravenous) dose of the alpha… (More)
Is this relevant?