Clodronic Acid

Known as: (Dichloro-phosphono-methyl)-phosphonic acid, (Dichloromethylene)bisphosphonic Acid, Acid, Dichloromethanediphosphonic 
A first-generation bisphosphonate with anti-resorptive and anti-hypercalcemic activities. Clodronic acid adsorbs onto the surface of the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Bisphosphonates reduce the risk of skeletal events in patients with malignant bone disease, and zoledronic acid has… (More)
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Highly Cited
2003
Highly Cited
2003
Alveolar macrophages (AMs) are considered major effector cells in host defense against respiratory tract infections by virtue of… (More)
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Highly Cited
1999
Highly Cited
1999
The roles played by resident macrophages (Mphi) and mast cells (MCs) in polymorphonuclear leukocyte (PMN) accumulation and… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Bisphosphonates are effective against the increased bone resorption caused by certain diseases because they inhibit… (More)
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Highly Cited
1998
Highly Cited
1998
Organ-specific autoimmune diseases are characterized by infiltrates, including T lymphocytes and activated macrophages… (More)
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Highly Cited
1998
Highly Cited
1998
Early impairment of islet function and graft loss limit the success of allogeneic islet transplantation. Nonspecific inflammatory… (More)
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Highly Cited
1997
Highly Cited
1997
Clodronate, alendronate, and other bisphosphonates are widely used in the treatment of bone diseases characterized by excessive… (More)
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Highly Cited
1993
Highly Cited
1993
Class II major histocompatibility complex (Ia)-bearing dendritic cells (DC) from airway epithelium and lung parenchyma express… (More)
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Highly Cited
1990
Highly Cited
1990
Almost 50% of the cells infiltrating the central nervous system (CNS) of animals with experimental allergic encephalomyelitis… (More)
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Highly Cited
1986
Highly Cited
1986
Pretreatment of a long bone explant with P-C-P can prevent the osteoclastic resorption of its mineralized matrix, when it is… (More)
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