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Clodronic Acid

Known as: (Dichloro-phosphono-methyl)-phosphonic acid, (Dichloromethylene)bisphosphonic Acid, Acid, Dichloromethanediphosphonic 
A first-generation bisphosphonate with anti-resorptive and anti-hypercalcemic activities. Clodronic acid adsorbs onto the surface of the… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (2)

Bone Density Conservation AgentsClodronate

Narrower (3)

Bonefosdifluoromethylene diphosphonatedifluoromethylenesulfonic acid
CLODRONATE DISODIUM 60 mg in 1 mL INTRAMUSCULAR INJECTION, SOLUTION [OSPHOS]Clodronate DisodiumIn Bloodagonists

Papers overview

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Highly Cited
2006
Highly Cited
2006
Structural and magnetic resolution of a two-step full spin-crossover transition in a dinuclear iron(II) pyridyl-bridged compound.
A dinuclear iron(II) complex containing the new pyridyl bridging ligand, 2,5-di(2',2''-dipyridylamino)pyridine (ddpp) has been… 
Highly Cited
2000
Highly Cited
2000
Pig islet xenograft rejection is markedly delayed in macrophage‐depleted mice: a study in streptozotocin diabetic animals
Abstract: The present study aimed to evaluate the effect of depletion of macrophages and/or natural killer (NK) cells on islet… 
Highly Cited
1999
Highly Cited
1999
Macrophage depletion alters vein graft intimal hyperplasia.
1997
1997
Elimination of resident macrophages from the livers and spleens of immune mice impairs acquired resistance against a secondary Listeria monocytogenes infection
During a secondary Listeria monocytogenes infection in mice, the bacteria are eliminated more rapidly from the liver and spleen… 
Highly Cited
1993
Highly Cited
1993
Liposome-mediated macrophage depletion: an experimental approach to study the role of testicular macrophages in the rat.
Liposome-entrapped dichloromethylene diphosphonate was injected locally into the right testes of adult rats. This treatment… 
Highly Cited
1986
Highly Cited
1986
Influence of carriers on the development and localization of anti‐2,4,6‐trinitrophenyl (TNP) antibody‐forming cells in the murine spleen: II. Suppressed antibody response to TNP‐Ficoll after…
The macrophages in the marginal zones in mice spleens were eliminated by i.v. injection of dichloromethylene diphosphonate… 
1981
1981
A comparison of skeletal uptakes of three diphosphonates by whole-body retention: concise communication.
Twenty normal volunteers had measurements of 24-hr whole-body retention (WBR) of three structurally related Tc-99m-labeled… 
Highly Cited
1981
Highly Cited
1981
The effects of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on collagen synthesis by rabbit articular chondrocytes and rat bone cells.
Investigations were performed to assess the effects of dichloromethanediphosphonate on the synthesis of collagen by (1) isolated… 
1978
1978
Comparative effects of cetaben (PHB) and dichlormethylene diphosphonate (Cl2MDP) on the development of atherosclerosis in the cynomolgus monkey.
Highly Cited
1974
Highly Cited
1974
The pyrophosphatase and (Ca2+-Mg2+)-ATPase activity of purified calf bone alkaline phosphatase.
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