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Clodronate

Known as: CLOD 
A nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate disodium binds to calcium and inhibits osteoclastic bone… 
National Institutes of Health

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7 relations

Narrower (6)

BonefosClasteonClodronate DisodiumClodronic Acid
clodronate/mitoxantrone/prednisone

Papers overview

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Highly Cited
2010
Highly Cited
2010
Growth Factors , Cytokines , Cell Cycle Molecules Contribution of Macrophages to Angiogenesis Induced by Vascular Endothelial Growth Factor Receptor-3-Specific Ligands
From the Schepens Eye Research Institute,* Harvard Medical School, Boston, Massachusetts; the Department of Ophthalmology… 
Review
2008
Review
2008
Emerging role of bisphosphonates in the clinic--antitumor activity and prevention of metastasis to bone.
Highly Cited
2005
Highly Cited
2005
Simultaneous enantioseparation and tandem UV-MS detection of eight beta-blockers in micellar electrokinetic chromatography using a chiral molecular micelle.
The feasibility of using a new and more versatile polymeric chiral surfactant, i.e., poly(sodium N-undecenoxy carbonyl-L… 
Review
2000
Review
2000
Oral bisphosphonates
This study was conducted to review the efficacy and safety of oral bisphosphonates for the treatment of bone metastases in cancer… 
Highly Cited
1998
Highly Cited
1998
Effects of tiludronate and ibandronate on the secretion of proinflammatory cytokines and nitric oxide from macrophages in vitro.
Highly Cited
1997
Highly Cited
1997
Human Neutrophil Collagenase MMP-8 in Peri-implant Sulcus Fluid and its Inhibition by Clodronate
The exact molecular mechanisms of the loosening of a dental implant are not well-known. The characteristics of implant sulci are… 
Highly Cited
1996
Highly Cited
1996
Calcitonin promotes osteoclast survival in vitro
Highly Cited
1995
Highly Cited
1995
Cyclical clodronate is effective in preventing postmenopausal bone loss: A comparative study with transcutaneous hormone replacement therapy
An investigative study was carried out for 2 years involving 124 randomly selected early postmenopausal women with spine bone… 
Highly Cited
1992
Highly Cited
1992
Effect of oral clodronate on bone pain
Although osteosclerotic metastases are characteristic of prostatic carcinoma, bone resorption is also accelerated. Since… 
Highly Cited
1987
Highly Cited
1987
Treatment of skeletal disease in breast cancer: a controlled clodronate trial.
Normocalcaemic breast cancer patients with progressive osteolytic bone metastases were treated with clodronate 1.6 g/day (17) or… 
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