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Clevudine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-, 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine, 1-(2-fluoro-5-methyl-beta,L-arabinofuranosyl)uracil 
A synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UNLABELLED Clevudine (Revovir), a pyrimidine nucleoside analogue, is a recently introduced antiviral drug. Clinical trials have… Expand
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2009
2009
Clevudine (L-FMAU) is a thymidine l-nucleoside analogue that was recently introduced for the treatment of chronic hepatitis B… Expand
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Review
2008
Review
2008
Increased cellular proliferation is an integral part of the cancer phenotype. Several in vitro assays have been developed to… Expand
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Review
2008
Review
2008
The evaluation of primary brain tumor is challenging. Neuroimaging plays a significant role. At diagnosis, imaging is needed to… Expand
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Highly Cited
2007
Highly Cited
2007
UNLABELLED Clevudine is a pyrimidine analogue with potent and sustained antiviral activity against HBV. The present study… Expand
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Highly Cited
2007
Highly Cited
2007
UNLABELLED Clevudine is a pyrimidine analog with potent and sustained antiviral activity against HBV. In the present study, we… Expand
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Highly Cited
2003
Highly Cited
2003
UNLABELLED The use of radiolabeled thymidine (TdR) and thymidine analogs as PET-based tracers of tumor growth rate is based on… Expand
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Highly Cited
1998
Highly Cited
1998
We report a series of studies that assess the feasibility and sensitivity of imaging of herpes virus type one thymidine kinase… Expand
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Highly Cited
1996
Highly Cited
1996
The thymidine analog fialuridine deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) was toxic in trials for chronic… Expand
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1995
1995
We have explored the mechanism(s) related to FIAU-induced liver toxicity, particularly focusing on its effect on mitochondrial… Expand
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