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Clevudine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-, 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine, 1-(2-fluoro-5-methyl-beta,L-arabinofuranosyl)uracil 
A synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites… 
National Institutes of Health

Related topics

Related topics

4 relations
5-methyl-2'-fluoroarauracilanalogs & derivatives

Broader (2)

Antiviral AgentsArabinofuranosyluracil

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Imaging DNA synthesis in vivo with 18F-FMAU and PET.
UNLABELLED We imaged DNA synthesis in vivo with PET and (18)F-1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)thymine (FMAU), which… 
Highly Cited
2004
Highly Cited
2004
Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography.
Highly Cited
2002
Highly Cited
2002
Phosphorylation of Pyrimidine Deoxynucleoside Analog Diphosphates
d-Nucleoside analogs, which are in the natural configuration, as well as the l-nucleoside analogs, are clinically relevant… 
Highly Cited
2002
Highly Cited
2002
Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic…
ABSTRACT Woodchucks chronically infected with the woodchuck hepatitis virus (WHV) were treated with the antiviral drug 1-(2… 
Highly Cited
2002
Highly Cited
2002
Rat studies comparing 11C-FMAU, 18F-FLT, and 76Br-BFU as proliferation markers.
UNLABELLED We analyzed and compared 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-[methyl-(11)C]thymine ((11)C-FMAU), 3'-deoxy-3… 
Highly Cited
2000
Highly Cited
2000
In vivo imaging of herpes simplex virus type 1 thymidine kinase gene expression: early kinetics of radiolabelled FIAU
Abstract.Previous studies have shown that the herpes simplex virus type 1 thymidine kinase gene (HSV1-tk), in combination with… 
Highly Cited
1995
Highly Cited
1995
Synthesis of 2'-fluoro-5-[11C]-methyl-1-beta-D-arabinofuranosyluracil ([11C]-FMAU): a potential nucleoside analog for in vivo study of cellular proliferation with PET.
Highly Cited
1993
Highly Cited
1993
Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.
A number of 5-heteroaromatic-substituted 2'-deoxyuridines were synthesized from 5-iodo-2'-deoxyuridine using tetraorganotin… 
Highly Cited
1989
Highly Cited
1989
Partial transcription map of Marek's disease herpesvirus in lytically infected cells and lymphoblastoid cell lines
Marek's disease herpesvirus (MDV) can cause either a productive‐restrictive or lytic infection, a latent infection or can… 
Highly Cited
1983
Highly Cited
1983
Distribution, Metabolism, and Excretion of 1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)thymine and 1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)-5-iodocytosine
1-(2-Fluoro-2-deoxy-β-d-arabinofuranosyl)thymine (FMAU) and 1-(2-fluoro-2-deoxy-β-d-arabinofuranosyl)-5-iodocytosine (FIAC) are… 
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