Clevudine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-, 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine, 1-(2-fluoro-5-methyl-beta,L-arabinofuranosyl)uracil 
A synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
0102019682018

Papers overview

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2010
2010
BACKGROUND & AIMS The aim of this study was to define the clinical, biochemical, and pathological characteristics of myopathy… (More)
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2009
2009
Clevudine (L-FMAU) is a thymidine l-nucleoside analogue that was recently introduced for the treatment of chronic hepatitis B… (More)
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2007
2007
UNLABELLED Clevudine is a pyrimidine analogue with potent and sustained antiviral activity against HBV. The present study… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations within the hepatitis B virus (HBV) polymerase gene conferring drug-resistance are selected during prolonged lamivudine… (More)
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2004
2004
3'-Deoxy-3'-[F-18]fluorothymidine (FLT) is under clinical evaluation as a metabolic probe for imaging cell proliferation in vivo… (More)
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Highly Cited
2003
Highly Cited
2003
UNLABELLED The use of radiolabeled thymidine (TdR) and thymidine analogs as PET-based tracers of tumor growth rate is based on… (More)
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Highly Cited
2001
Highly Cited
2001
Hepadnaviruses replicate by reverse transcription, which takes place in the cytoplasm of the infected hepatocyte. Viral RNAs… (More)
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Highly Cited
1999
Highly Cited
1999
The feasibility of noninvasive imaging of adenoviral-mediated herpes virus type one thymidine kinase (HSV1-tk) gene transfer and… (More)
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Highly Cited
1998
Highly Cited
1998
We report a series of studies that assess the feasibility and sensitivity of imaging of herpes virus type one thymidine kinase… (More)
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1996
1996
The thymidine analog fialuridine deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) was toxic in trials for chronic… (More)
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