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Clevudine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-, 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine, 1-(2-fluoro-5-methyl-beta,L-arabinofuranosyl)uracil 
A synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Increased cellular proliferation is an integral part of the cancer phenotype. Several in vitro assays have been developed to… Expand
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Highly Cited
2005
Highly Cited
2005
Mutations within the hepatitis B virus (HBV) polymerase gene conferring drug‐resistance are selected during prolonged lamivudine… Expand
Highly Cited
2001
Highly Cited
2001
ABSTRACT Hepadnaviruses replicate by reverse transcription, which takes place in the cytoplasm of the infected hepatocyte. Viral… Expand
Highly Cited
2000
Highly Cited
2000
Several nucleoside analogues (penciclovir, lobucavir, dioxalane guanine [DXG], 1‐β‐2,6‐diaminopurine dioxalane [DAPD], L‐FMAU… Expand
Highly Cited
1998
Highly Cited
1998
We report a series of studies that assess the feasibility and sensitivity of imaging of herpes virus type one thymidine kinase… Expand
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Highly Cited
1996
Highly Cited
1996
The thymidine analog fialuridine deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) was toxic in trials for chronic… Expand
Highly Cited
1996
Highly Cited
1996
Since 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU) has been shown to be a potent anti-HBV agent in vitro, it was of… Expand
Highly Cited
1996
Highly Cited
1996
2'-Fluoro-5-methyl-beta-L-arabinofuranosyl uracil (L-FMAU) was discovered to have potent antiviral activity against hepatitis B… Expand
Highly Cited
1995
Highly Cited
1995
A novel anti-hepatitis B virus (anti-HBV) agent, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU), was synthesized and… Expand
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Highly Cited
1981
Highly Cited
1981
Potential antiviral nucleoside analogs 1-beta-D-arabinofuranosylthymine, the 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl… Expand
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