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Ciprofloxacin

Known as: 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, Ciprofloxacin [Chemical/Ingredient], Ciprofloxacine 
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Persisters are specialized survivor cells that arise in populations of E. coli after antibiotic-mediated DNA damage induces the… 
Highly Cited
2007
Highly Cited
2006
Highly Cited
2006
ABSTRACT Among 313 Enterobacteriaceae from the United States with a ciprofloxacin MIC of ≥0.25 μg/ml and reduced susceptibility… 
Highly Cited
2004
Highly Cited
2004
Highly Cited
2003
Highly Cited
2003
ABSTRACT The roles of slow antibiotic penetration, oxygen limitation, and low metabolic activity in the tolerance of Pseudomonas… 
Highly Cited
2000
Highly Cited
2000
ABSTRACT The penetration of two antibiotics, ampicillin and ciprofloxacin, through biofilms developed in an in vitro model system… 
Highly Cited
1998
Highly Cited
1996
Highly Cited
1996
The aim of this study was to clarify the antibacterial effect of a mixture of ciprofloxacin, metronidazole and minocycline, with… 
Highly Cited
1993
Highly Cited
1993
Seventy-four acutely ill patients were treated with intravenous ciprofloxacin at dosages ranging between 200 mg every 12 h and… 
Review
1988
Review
1988
Ciprofloxacin is one of a new generation of fluorinated quinolones structurally related to nalidixic acid. The primary mechanism…