Ciprofloxacin

Known as: 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, Ciprofloxacin [Chemical/Ingredient], Ciprofloxacine 
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The indigenous human microbiota is essential to the health of the host. Although the microbiota can be affected by many features… (More)
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Highly Cited
2010
Highly Cited
2010
Bacteria induce stress responses that protect the cell from lethal factors such as DNA-damaging agents. Bacterial populations… (More)
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Highly Cited
2008
Highly Cited
2008
The human intestinal microbiota is essential to the health of the host and plays a role in nutrition, development, metabolism… (More)
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Highly Cited
2006
Highly Cited
2006
Among 313 Enterobacteriaceae from the United States with a ciprofloxacin MIC of >/=0.25 microg/ml and reduced susceptibility to… (More)
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Highly Cited
2003
Highly Cited
2003
The roles of slow antibiotic penetration, oxygen limitation, and low metabolic activity in the tolerance of Pseudomonas… (More)
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Highly Cited
2000
Highly Cited
2000
The penetration of two antibiotics, ampicillin and ciprofloxacin, through biofilms developed in an in vitro model system was… (More)
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Highly Cited
2000
Highly Cited
2000
A prospective study of Klebsiella pneumoniae bacteremia was performed in 12 hospitals in 7 countries. Of 452 episodes of… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES To determine whether antimicrobial prophylaxis could prevent infections after transrectal needle biopsy of the… (More)
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Highly Cited
1993
Highly Cited
1993
Seventy-four acutely ill patients were treated with intravenous ciprofloxacin at dosages ranging between 200 mg every 12 h and… (More)
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Highly Cited
1983
Highly Cited
1983
A 500-mg dose of the quinoline ciprofloxacin was administered orally to each of six healthy male volunteers, after which the… (More)
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