Chronic myeloproliferative disorder

Known as: Myeloproliferative Disorder, MPD, Myeloproliferative Neoplasm 
A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
020040019532017

Papers overview

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Highly Cited
2010
Highly Cited
2010
The oncogenetic events that transform chronic myeloproliferative neoplasms (MPN) to acute myeloid leukemias (AML) are not well… (More)
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Highly Cited
2009
Highly Cited
2009
Chromosomal abnormalities are frequent in myeloid malignancies, but in most cases of myelodysplasia (MDS) and myeloproliferative… (More)
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Highly Cited
2008
Highly Cited
2008
Reporting of myelodysplastic syndromes (MDSs) and chronic myeloproliferative disorders (CMDs) to population-based cancer… (More)
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Highly Cited
2007
Highly Cited
2007
JAK2V617F and MPLW515L/K represent recently identified mutations in myeloproliferative disorders (MPD) that cause dysregulated… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Thrombosis of splanchnic or cerebral veins is a typical manifestation of polycythemia vera (PV) or essential… (More)
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Highly Cited
2006
Highly Cited
2006
The diagnosis of an underlying chronic myeloproliferative disorder (CMPD) is often problematic in patients with primary… (More)
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Highly Cited
2005
Highly Cited
2005
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the importance of aberrant… (More)
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Highly Cited
2005
Highly Cited
2005
A somatic mutation in the JH2 autoinhibitory domain of the Janus kinase 2 (JAK2) tyrosine kinase was recently described in… (More)
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Highly Cited
2004
Highly Cited
2004
The AP-1 transcription factor JunB is a transcriptional regulator of myelopoiesis. Inactivation of JunB in postnatal mice results… (More)
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Highly Cited
1987
Highly Cited
1987
We report on investigations aimed at detecting mutated RAS genes in a variety of preleukemic disorders and leukemias of myeloid… (More)
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