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Chronic myeloproliferative disorder

Known as: Myeloproliferative Disorder, MPD, Myeloproliferative Neoplasm 
A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Myeloproliferative neoplasms (MPNs) are clonal disorders characterized by excessive production of mature blood cells. In the… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Myelofibrosis is a Philadelphia chromosome–negative myeloproliferative neoplasm associated with cytopenias… Expand
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Review
2010
Review
2010
Myeloproliferative neoplasms (MPNs) originate from genetically transformed hematopoietic stem cells that retain the capacity for… Expand
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Highly Cited
2010
Highly Cited
2010
Constitutive JAK2 activation in hematopoietic cells by the JAK2V617F mutation recapitulates myeloproliferative neoplasm (MPN… Expand
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Highly Cited
2009
Highly Cited
2009
Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified… Expand
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Highly Cited
2008
Highly Cited
2008
Reporting of myelodysplastic syndromes (MDSs) and chronic myeloproliferative disorders (CMDs) to population-based cancer… Expand
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Highly Cited
2006
Highly Cited
2006
Background The JAK2V617F allele has recently been identified in patients with polycythemia vera (PV), essential thrombocytosis… Expand
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Highly Cited
2006
Highly Cited
2006
Haematopoietic stem cells (HSCs) must achieve a balance between quiescence and activation that fulfils immediate demands for… Expand
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Highly Cited
2005
Highly Cited
2005
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the importance of aberrant… Expand
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Highly Cited
2004
Highly Cited
2004
The AP-1 transcription factor JunB is a transcriptional regulator of myelopoiesis. Inactivation of JunB in postnatal mice results… Expand
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