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Chronic myeloproliferative disorder
Known as:
Myeloproliferative Disorder
, MPD
, Myeloproliferative Neoplasm
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A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic…
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National Institutes of Health
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Related topics
Related topics
14 relations
Bone Marrow
Bone marrow stem cell
EPSTI1 gene
EPSTI1 wt Allele
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Broader (1)
Myeloproliferative disease
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis.
S. Verstovsek
,
H. Kantarjian
,
+10 authors
A. Tefferi
New England Journal of Medicine
2010
Corpus ID: 19369678
BACKGROUND Myelofibrosis is a Philadelphia chromosome–negative myeloproliferative neoplasm associated with cytopenias…
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Review
2010
Review
2010
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1
A. Tefferi
Leukemia
2010
Corpus ID: 8883293
Myeloproliferative neoplasms (MPNs) originate from genetically transformed hematopoietic stem cells that retain the capacity for…
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Highly Cited
2010
Highly Cited
2010
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms.
A. Quintás-Cardama
,
K. Vaddi
,
+18 authors
S. Verstovsek
Blood
2010
Corpus ID: 15552112
Constitutive JAK2 activation in hematopoietic cells by the JAK2V617F mutation recapitulates myeloproliferative neoplasm (MPN…
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Highly Cited
2009
Highly Cited
2009
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
O. Abdel-Wahab
,
A. Mullally
,
+21 authors
R. Levine
Blood
2009
Corpus ID: 2177504
Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified…
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Highly Cited
2008
Highly Cited
2008
Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs.
D. Rollison
,
N. Howlader
,
+5 authors
A. List
Blood
2008
Corpus ID: 183832
Reporting of myelodysplastic syndromes (MDSs) and chronic myeloproliferative disorders (CMDs) to population-based cancer…
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Highly Cited
2006
Highly Cited
2006
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
Y. Pikman
,
Benjamin H. Lee
,
+14 authors
R. Levine
PLoS Medicine
2006
Corpus ID: 15640328
Background The JAK2V617F allele has recently been identified in patients with polycythemia vera (PV), essential thrombocytosis…
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Highly Cited
2006
Highly Cited
2006
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Jiwang Zhang
,
J. Grindley
,
+9 authors
Linheng Li
Nature
2006
Corpus ID: 4428302
Haematopoietic stem cells (HSCs) must achieve a balance between quiescence and activation that fulfils immediate demands for…
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Highly Cited
2005
Highly Cited
2005
Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders.
A. Jones
,
S. Kreil
,
+22 authors
N. Cross
Blood
2005
Corpus ID: 43605204
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the importance of aberrant…
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Review
1986
Review
1986
The clinical phenomenology of multiple personality disorder: review of 100 recent cases.
F. Putnam
,
J. Guroff
,
E. Silberman
,
L. Barban
,
R. Post
Journal of Clinical Psychiatry
1986
Corpus ID: 35893419
The clinical syndrome of multiple personality disorder (MPD) is an unusual dissociative condition that has been poorly…
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Highly Cited
1984
Highly Cited
1984
Leukemia
C. Geary
British Journal of Cancer
1984
Corpus ID: 215711124
Your friend is lucky to have someone like you who wants to learn more about what they’re going through. Leukemia is a general…
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