Chromothripsis

Known as: Chromothripsis [Disease/Finding], Shattering, Chromosome, Chromothripses 
A cytogenetic abnormality characterized by the occurrence of a large number of chromosomal rearrangements that are restricted to sites in one or a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
0102019542016

Papers overview

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2016
2016
Chromothripsis is a recently discovered form of genomic instability, characterized by tens to hundreds of clustered DNA… (More)
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Highly Cited
2015
Highly Cited
2015
Genome sequencing has uncovered a new mutational phenomenon in cancer and congenital disorders called chromothripsis… (More)
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Highly Cited
2015
Highly Cited
2015
Telomere crisis occurs during tumorigenesis when depletion of the telomere reserve leads to frequent telomere fusions. The… (More)
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2015
2015
A remarkable observation emerging from recent cancer genome analyses is the identification of chromothripsis as a one-off genomic… (More)
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2013
2013
Chromothripsis, a newly discovered type of complex genomic rearrangement, has been implicated in the evolution of several types… (More)
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2013
2013
The acquisition of massive but localized chromosome translocations, a phenomenon termed chromothripsis, has received widespread… (More)
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Highly Cited
2012
Highly Cited
2012
Chromothripsis represents a novel phenomenon in the structural variation landscape of cancer genomes. Here, we analyze the… (More)
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Highly Cited
2011
Highly Cited
2011
Multiple myeloma (MM) develops from a premalignant plasma cell proliferative disorder, and with time can progress to a more… (More)
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Highly Cited
2011
Highly Cited
2011
A variety of mutational mechanisms shape the dynamic architecture of human genomes and occasionally result in congenital defects… (More)
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Highly Cited
2011
Highly Cited
2011
Structural rearrangements form a major class of somatic variation in cancer genomes. Local chromosome shattering, termed… (More)
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