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Chromosomes, Human, Pair 4
Known as:
4 chromosome
, Chromosome 4
The designation for each member of the fourth largest human autosomal chromosome pair. Chromosome 4 spans more than 186 million base pairs and…
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National Institutes of Health
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Related topics
Related topics
15 relations
Chromatin
Chromosome 4 Short Arm
Loss of Chromosome 4
Microbiological
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Narrower (3)
Chromosome 4 short arm deletion
Chromosome 4, trisomy 4q
Ring chromosome 4 syndrome
Broader (1)
Chromosomes, Human, 4-5
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The zebrafish reference genome sequence and its relationship to the human genome
K. Howe
,
M. Clark
,
+174 authors
D. Stemple
Nature
2013
Corpus ID: 205233806
Zebrafish have become a popular organism for the study of vertebrate gene function. The virtually transparent embryos of this…
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Highly Cited
2002
Highly Cited
2002
Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites
B. Czermin
,
R. Melfi
,
D. Mccabe
,
Volker Seitz
,
A. Imhof
,
V. Pirrotta
Cell
2002
Corpus ID: 17868014
Highly Cited
1998
Highly Cited
1998
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.
R. Allikmets
,
L. Schriml
,
+4 authors
Dean
Cancer Research
1998
Corpus ID: 315413
We characterized a new human ATP-binding cassette (ABC) transporter gene that is highly expressed in the placenta. The gene, ABCP…
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Highly Cited
1997
Highly Cited
1997
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M. Polymeropoulos
,
C. Lavedan
,
+17 authors
R. Nussbaum
Science
1997
Corpus ID: 42315772
Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern…
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Highly Cited
1994
Highly Cited
1994
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.
M. Vitaterna
,
D. P. King
,
+8 authors
J. Takahashi
Science
1994
Corpus ID: 31473202
In a search for genes that regulate circadian rhythms in mammals, the progeny of mice treated with N-ethyl-N-nitrosourea (ENU…
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Highly Cited
1994
Highly Cited
1994
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
R. Shiang
,
L. Thompson
,
+5 authors
J. Wasmuth
Cell
1994
Corpus ID: 20325070
Highly Cited
1992
Highly Cited
1992
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
Y. Gu
,
Tomonori Nakamura
,
+5 authors
E. Canaani
Cell
1992
Corpus ID: 6257922
Highly Cited
1988
Highly Cited
1988
Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.
D. Pinkel
,
J. Landegent
,
+4 authors
J. Gray
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 34219596
Chromosomes can be specifically stained in metaphase spreads and interphase nuclei by in situ hybridization with entire…
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Highly Cited
1987
Highly Cited
1987
Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
Y. Yarden
,
W. Kuang
,
+7 authors
A. Ullrich
EMBO Journal
1987
Corpus ID: 4310608
Structural features of v‐kit, the oncogene of HZ4 feline sarcoma virus, suggested that this gene arose by transduction and…
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Highly Cited
1983
Highly Cited
1983
A polymorphic DNA marker genetically linked to Huntington's disease
J. Gusella
,
N. Wexler
,
+11 authors
Joseph B. Martin
Nature
1983
Corpus ID: 4320711
Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The…
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