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Chromosomes, Human, Pair 4

Known as: 4 chromosome, Chromosome 4 
The designation for each member of the fourth largest human autosomal chromosome pair. Chromosome 4 spans more than 186 million base pairs and… 
National Institutes of Health

Related topics

Related topics

15 relations
ChromatinChromosome 4 Short ArmLoss of Chromosome 4Microbiological

Narrower (3)

Chromosome 4 short arm deletionChromosome 4, trisomy 4qRing chromosome 4 syndrome

Broader (1)

Chromosomes, Human, 4-5

Papers overview

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Highly Cited
2002
Highly Cited
2002
Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu
The conditional expression of activated HER2/neu gene under its endogenous promoter in the mammary epithelium of the mouse… 
Highly Cited
1997
Highly Cited
1997
Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin.
Cortistatin is a 14-residue putative neuropeptide with strong structural similarity to somatostatin and is expressed… 
Highly Cited
1995
Highly Cited
1995
Cloning and characterization of murine p16INK4a and p15INK4b genes.
Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6… 
Highly Cited
1992
Highly Cited
1992
Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression
Phototransduction in retinal rods involves a G-protein-mediated signaling cascade that leads to cGMP hydrolysis and the closure… 
Highly Cited
1991
Highly Cited
1991
Molecular confirmation of Wolf-Hirschhorn syndrome with a subtle translocation of chromosome 4.
Wolf-Hirschhorn syndrome is a clinically recognizable, multiple congenital anomaly syndrome usually associated with terminal… 
Highly Cited
1989
Highly Cited
1989
Segregation of the Huntington disease region of human chromosome 4 in a somatic cell hybrid.
Highly Cited
1989
Highly Cited
1989
Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.
Recombinant inbred strain and interspecific backcross mice were used to create a molecular genetic linkage map of the distal… 
Highly Cited
1988
Highly Cited
1988
Microcloning reveals a high frequency of repetitive sequences characteristic of chromosome 4 and the beta-heterochromatin of Drosophila melanogaster.
Microdissection and microcloning of the euchromatin-heterochromatin transition region of the Drosophila melanogaster polytene X… 
Highly Cited
1986
Highly Cited
1986
Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas.
The murine lck gene is closely related to a family of cellular protooncogenes and encodes a lymphocyte-specific, membrane… 
Highly Cited
1982
Highly Cited
1982
The analysis of malignancy by cell fusion. IX. Re-examination and clarification of the cytogenetic problem.
Previous experiments with crosses between malignant and diploid mouse cells had shown that the reappearance of malignancy in… 
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