Chromosomes, Human, Pair 14

Known as: 14 chromosome, Chromosome 14 
The designation for each member of the fourteenth largest human autosomal chromosome pair. Chromosome 14 spans about 105 million base pairs and… (More)
National Institutes of Health

Related topics

Related topics

35 relations
AP5M1 geneATG2B geneCOX16 geneChromatin
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Narrower (4)

Chromosome 14, trisomy mosaicRing Chromosome 14 SyndromeUniparental disomy, paternal, chromosome 14chromosome 14 trisomy syndrome

Broader (1)

Chromosomes, Human, 13-15

Papers overview

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Highly Cited
2011
Highly Cited
2011
FLASH: fast length adjustment of short reads to improve genome assemblies
MOTIVATION Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome… (More)
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Highly Cited
2008
Highly Cited
2008
Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes
Human chromosome 14q32.2 carries a cluster of imprinted genes including paternally expressed genes (PEGs) such as DLK1 and RTL1… (More)
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Highly Cited
2002
Highly Cited
2002
Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity.
Preadipocyte factor 1 (Pref-1/Dlk1) inhibits in vitro adipocyte differentiation and has been recently reported to be a paternally… (More)
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Highly Cited
2001
Highly Cited
2001
Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.
At least two distinct recurrent chromosomal translocations have been implicated in the pathogenesis of MALT lymphoma. The first… (More)
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Highly Cited
2001
Highly Cited
2001
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia
FISH identified a cryptic t(5;14)(q35;q32) in T acute lymphoblastic leukemia (ALL), whereas it was not observed in B ALL samples… (More)
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Highly Cited
2000
Highly Cited
2000
Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation.
The evolution of genomic imprinting in mammals occurred more than 100 million years ago, and resulted in the formation of genes… (More)
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Highly Cited
1999
Highly Cited
1999
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
Missense mutations in the human presenilin-1 (PS1) gene, which is found on chromosome 14, cause early-onset familial Alzheimer’s… (More)
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Review
1999
Review
1999
Cellular mechanisms of beta-amyloid production and secretion.
The major constituent of senile plaques in Alzheimer's disease is a 42-aa peptide, referred to as beta-amyloid (Abeta). Abeta is… (More)
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Highly Cited
1997
Highly Cited
1997
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells.
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis… (More)
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Highly Cited
1985
Highly Cited
1985
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.
Specific chromosomal translocations found in distinct neoplasms suggest that genes that flank such breakpoints play a critical… (More)
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