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Chromosomes, Human, Pair 10

Known as: 10 chromosome, Chromosome 10 
The designation for each member of the tenth largest human autosomal chromosome pair. Chromosome 10 spans about 135 million base pairs and represents… Expand
National Institutes of Health

Related topics

Related topics

20 relations
10qBannayan-Riley-Ruvalcaba SyndromeChromatinChromosome 10 Short Arm
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Narrower (5)

Chromosome 10 ringChromosome 10, monosomy 10qChromosome 10, trisomy 10pChromosome 10q duplication syndrome
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Broader (2)

Chromosomes, HumanChromosomes, Human, 6-12 and X

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Targeting PI3K in cancer: mechanisms and advances in clinical trials
Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is one of the most important… Expand
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Review
2018
Review
2018
Biomechanics and mechanical signaling in the ovary: a systematic review
PurposeMammalian oogenesis and folliculogenesis share a dynamic connection that is critical for gamete development. For… Expand
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Highly Cited
2008
Highly Cited
2008
Multiple loci identified in a genome-wide association study of prostate cancer
We followed our initial genome-wide association study (GWAS) of 527,869 SNPs on 1,172 individuals with prostate cancer and 1,157… Expand
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Highly Cited
2008
Highly Cited
2008
NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.
Phosphatidylinositol-3-kinase (PI3K) pathway deregulation is a common event in human cancer, either through inactivation of the… Expand
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Highly Cited
2006
Highly Cited
2006
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.
BACKGROUND & AIMS Micro-RNA (miRNA) are endogenous regulatory RNA molecules that modulate gene expression. Alterations in miRNA… Expand
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Highly Cited
2003
Highly Cited
2003
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
Two substrates of insulin-degrading enzyme (IDE), amyloid β-protein (Aβ) and insulin, are critically important in the… Expand
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Review
2000
Review
2000
The Multiple Roles of PTEN in Tumor Suppression
Abstract In his celebrated monolog, the Shakespearean hero Hamlet clearly identified two extreme remedies: "To die: to sleep; no… Expand
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Highly Cited
1990
Highly Cited
1990
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
We have cloned a partial cDNA encoding murine stem cell factor (SCF) and show that the gene is syntenic with the Sl locus on… Expand
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Highly Cited
1990
Highly Cited
1990
The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus
Mutations at the steel locus (Sl) of the mouse affect the same cellular targets as mutations at the white spotting locus (W… Expand
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Highly Cited
1990
Highly Cited
1990
Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms
We have previously reported the identification of a novel mast cell growth factor (MGF) that was shown to be a ligand for c-kit… Expand
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