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Chromosomes, Artificial, Yeast

Known as: Artificial Chromosome, Yeast, YAC Vector, Artificial Chromosomes, Yeast 
A cloning vector based upon elements of yeast chromosomes. At a minimum these include: yeast telomeres, a yeast centromere, and a yeast autonomously… 
National Institutes of Health

Related topics

Related topics

12 relations
Chromosome MappingCloning, MolecularGenetic TechniquesGenomic Library

Broader (4)

ChromosomesChromosomes, ArtificialChromosomes, Fungalgenetic manipulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Incidence and clinical significance of 6q deletions in B cell chronic lymphocytic leukemia
Deletions affecting the long arm of chromosome 6 (6q) are among the most commonly observed chromosomal aberrations in lymphoid… 
Highly Cited
1999
Highly Cited
1999
Efficient and precise engineering of a 200 kb β-globin human/bacterial artificial chromosome in E. coli DH10B using an inducible homologous recombination system
Gene therapy studies require techniques that allow alteration of human genomic DNA sequences. Bacterial artificial chromosome… 
Highly Cited
1998
Highly Cited
1998
Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A.
The voltage-gated sodium channel SCN8A is associated with inherited neurological disorders in the mouse that include ataxia… 
Highly Cited
1995
Highly Cited
1995
Evidence of a locus for orofacial clefting on human chromosome 6p24 and STS content map of the region.
Orofacial clefting is genetically complex, no single gene being responsible for all forms. It can, however, result from a single… 
Highly Cited
1994
Highly Cited
1994
A novel gene encoding a B-box protein within the BRCA1 region at 17q21.1.
A novel cDNA clone was isolated using a polyclonal serum directed against partially purified ovarian carcinoma antigen CA125. The… 
Highly Cited
1993
Highly Cited
1993
A complete YAC contig of the Prader-Willi/Angelman chromosome region (15q11-q13) and refined localization of the SNRPN gene.
Highly Cited
1992
Highly Cited
1992
The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.
We have developed modifications to direct cDNA selection that allow the rapid and reproducible isolation of low abundance cDNAs… 
Highly Cited
1990
Highly Cited
1990
Genomic walking and sequencing by oligo-cassette mediated polymerase chain reaction.
Recently, a method named inverse PCR has been described by which genomic DNA sequences adjacent to a known (sequenced) locus can… 
Highly Cited
1979
Highly Cited
1979
Enhancement by interferon of natural killer cell activity in mice.
Highly Cited
1978
Highly Cited
1978
Higher antitumor efficacy of daunomycin when linked to dextran: in vivo and in vitro studies.
Daunomycin was coupled to dextrans of various molecular sizes. The binding to the dextran carriers augmented the therapeutic… 
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