Chromosomes, Artificial

Known as: Artificial Chromosome, Artificial chromosomes, Chromosome, Artificial 
DNA constructs that are composed of, at least, elements such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Shiaoching Gong,1 Martin Doughty,1 Carroll R. Harbaugh,4 Alexander Cummins,4 Mary E. Hatten,2 Nathaniel Heintz,3 and Charles R… (More)
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Highly Cited
2003
Highly Cited
2003
The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of… (More)
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Highly Cited
2000
Highly Cited
2000
A recombination system has been developed for efficient chromosome engineering in Escherichia coli by using electroporated linear… (More)
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Highly Cited
2000
Highly Cited
2000
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the… (More)
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Highly Cited
1999
Highly Cited
1999
We present a method to modify bacterial artificial chromosomes (BACs) resident in their host strain. The method is based on… (More)
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Highly Cited
1998
Highly Cited
1998
The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology… (More)
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Highly Cited
1998
Highly Cited
1998
To construct a mammalian artificial chromosome (MAC), telomere repeats and selectable markers were introduced into a 100 kb yeast… (More)
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Highly Cited
1996
Highly Cited
1996
Functional nuclei and mitotic spindles are shown to assemble around DNA-coated beads incubated in Xenopus egg extracts. Bipolar… (More)
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Highly Cited
1987
Highly Cited
1987
Fragments of exogenous DNA that range in size up to several hundred kilobase pairs have been cloned into yeast by ligating them… (More)
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Highly Cited
1983
Highly Cited
1983
Fifty-five-kilobase long artificial chromosomes containing cloned genes, replicators, centromeres and telomeres have been… (More)
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