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Chromosomal Instability

Known as: Chromosomal Instability [Disease/Finding], Instability, Chromosome, Chromosome instability 
The instability of chromosomes is attributed to the continuous formation of novel chromosome mutations. These mutations form at an elevated rate in… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Aberrant chromosomal architecture, ranging from small insertions or deletions to large chromosomal alterations, is one of the… Expand
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Review
2017
Review
2017
Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development… Expand
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Review
2017
Review
2017
Chromosomal aberrations during cell division represent one of the first recognized features of human cancer cells, and modern… Expand
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Review
2017
Review
2017
Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of… Expand
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Review
2016
Review
2016
Colorectal cancer (CRC) shows variable underlying molecular changes with two major mechanisms of genetic instability: chromosomal… Expand
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Highly Cited
2009
Highly Cited
2009
Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a… Expand
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Highly Cited
2007
Highly Cited
2007
Autophagy is a bulk degradation process that promotes survival under metabolic stress, but it can also be a means of cell death… Expand
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Highly Cited
2006
Highly Cited
2006
We developed a computational method to characterize aneuploidy in tumor samples based on coordinated aberrations in expression of… Expand
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Highly Cited
2005
Highly Cited
2005
To define the genetic requirements for pancreatic ductal adenocarcinoma (PDA), we have targeted concomitant endogenous expression… Expand
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Highly Cited
1997
Highly Cited
1997
It has long been considered that genetic instability is an integral component of human neoplasia1–3. In a small fraction of… Expand
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