FAQ

Chromosome Fragility

Known as: Chromosome Fragility [Disease/Finding], Chromosomal Fragility, Fragility, Chromosome 
Susceptibility of chromosomes to breakage leading to translocation; CHROMOSOME INVERSION; SEQUENCE DELETION; or other CHROMOSOME BREAKAGE related… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2017
02419742017

Related topics

Related topics

7 relations

Broader (1)

Chromosomal Instability
Chromosome BreakageChromosome Fragile SitesFragile X SyndromeTrinucleotide Repeat Expansion
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Chromosome Fragility
physiological aspects
Fragile X Syndrome
Chromosomal Instability
Chromosome Breakage
Chromosome Fragile Sites

Papers overview

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2017
2017
Genome Organization Drives Chromosome Fragility.
In this study, we show that evolutionarily conserved chromosome loop anchors bound by CCCTC-binding factor (CTCF) and cohesin are… (More)
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2017
2017
Giant Retroperitoneal Myxoid Liposarcomas, Survival in Chromosomal Fragility
Background: Primary retroperitoneal sarcomas are rare, corresponds 0.1 to 0.2 percent of all malignant lesions in adults and… (More)
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2015
2015
Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.
Secondary structure-forming DNA sequences such as CAG repeats interfere with replication and repair, provoking fork stalling… (More)
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2015
2015
Evidence for chromosome fragility at the frataxin locus in Friedreich ataxia.
Friedreich ataxia (FRDA) is a member of the Repeat Expansion Diseases, a group of genetic conditions resulting from an increase… (More)
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2013
2013
Risk factors for multiple malignancies in the head and neck.
OBJECTIVE To define the prognostic role of multiple epidemiological, clinical, and biological factors for the development of… (More)
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2009
2009
Genome-Organizing Factors Top2 and Hmo1 Prevent Chromosome Fragility at Sites of S phase Transcription
Specialized topoisomerases solve the topological constraints arising when replication forks encounter transcription. We have… (More)
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2007
2007
Replication-Dependent Mechanism of Chromosome Fragility at the Site of Inverted Repeats in Saccharomyces cerevisiae
Genome instability is linked to cancer and many hereditary diseases. Chromosomal aberrations are often associated with repeats… (More)
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2005
2005
Minor Physical Anomalies and Chromosomal Fragility as Potential Markers in Schizophrenia. Preliminary Report
In the present study, the authors investigated chromosomal fragility in patients with schizophrenia, and compared the patients… (More)
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1984
1984
Increased Chromosome Fragility of Donor Cells in Fanconi's Anemia after Bone Marrow Transplantation
Bone marrow transplantation appears to be an effective method of treatment of cases of Fanconi's anemia (FA) in the aplastic… (More)
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1974
1974
Microfluorometric Analysis of Sister Chromatid Exchanges, Indices of Chromosome Fragility
Quenching of 33258 Hoechst fluorescence by 5-bromodeoxyuridine incorporated into chromosomal DNA (S.A. Latt, P.N.A.S. 70:3395… (More)
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