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Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene
Sexual orientation and courtship behavior in Drosophila are regulated by fruitless (fru), the first gene in a branch of the sex-determination hierarchy functioning specifically in the central nervousExpand
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Gene Expression During the Life Cycle of Drosophila melanogaster
Molecular genetic studies of Drosophila melanogaster have led to profound advances in understanding the regulation of development. Here we report gene expression patterns for nearly one-third of allExpand
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Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides
The doublesex (dsx) gene regulates somatic sexual differentiation in both sexes in D. melanogaster. Two functional products are encoded by dsx: one product is expressed in females and represses maleExpand
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Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
Robust innate behaviours are attractive systems for genetically dissecting how environmental cues are perceived and integrated to generate complex behaviours. During courtship, Drosophila malesExpand
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Genes controlling essential cell-cycle functions in Drosophila melanogaster.
On the basis of the hypothesis that mutants in genes controlling essential cell cycle functions in Drosophila should survive up to the larval-pupal transition, 59 such 'late lethals' were screenedExpand
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The maleless protein associates with the X chromosome to regulate dosage compensation in drosophila
The maleless (mle) gene is one of four known regulatory loci required for increased transcription (dosage compensation) of X-linked genes in D. melanogaster males. A predicted mle protein (MLE)Expand
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Central Brain Neurons Expressing doublesex Regulate Female Receptivity in Drosophila
Drosophila melanogaster females respond to male courtship by either rejecting the male or allowing copulation. The neural mechanisms underlying these female behaviors likely involve the integrationExpand
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The evolutionary dynamics of sex determination.
REVIEW There is substantial cytogenetic data indicating that the process of sex determination can evolve relatively rapidly. However, recent molecular studies on the evolution of the regulatory genesExpand
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Sex in flies: the splice of life
The discovery that the primary transcripts of many genes are processed to produce more than one kind of messenger RNA focuses attention on the control of RNA processing as a developmental regulatoryExpand
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Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster.
Sex determination in Drosophila melanogaster is under the control of the X chromosome:autosome ratio and at least four major regulatory genes: transformer (tra), transformer-2 (tra-2), doublesexExpand
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