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Choline O-Acetyltransferase, human
Known as:
CHAT
, Choline O-Acetyltransferase
, CHOACTase
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Choline O-acetyltransferase (748 aa, ~83 kDa) is encoded by the human CHAT gene. This protein is involved in acetylcholine biosynthesis.
National Institutes of Health
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Related topics
Related topics
7 relations
Acetylation
CHAT gene
Cytoplasmic matrix
Enzyme Gene
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Broader (1)
Choline O-Acetyltransferase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Structure and Organization of the DrosophilaCholinergic Locus*
T. Kitamoto
,
Weiya Wang
,
P. Salvaterra
Journal of Biological Chemistry
1998
Corpus ID: 9173322
The Drosophila cholinergic locus is composed of two distinct genetic functions: choline acetyltransferase (ChAT; EC 2.3.1.6), the…
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1992
1992
Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions.
J. Toussaint
,
V. Geoffroy
,
+4 authors
J. Kempf
Genomics
1992
Corpus ID: 9838453
1989
1989
Purification and isolation of choline acetyltransferase from the electric organ of Torpedo marmorata by affinity chromatography.
A. Raeber
,
G. Riggio
,
P. Waser
European Journal of Biochemistry
1989
Corpus ID: 43269500
Choline acetyltransferase (EC 2.3.1.6) catalyzes the synthesis of the neurotransmitter acetylcholine from acetylcoenzyme A and…
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Highly Cited
1987
Highly Cited
1987
cDNA cloning and complete sequence of porcine choline acetyltransferase: in vitro translation of the corresponding RNA yields an active protein.
S. Berrard
,
Alexis Brice
,
Friedrich Lottspeich
,
Axel Braun
,
Y. Barde
,
Jacques Mallet
Proceedings of the National Academy of Sciences…
1987
Corpus ID: 2922073
A cDNA clone encoding the complete sequence of porcine choline acetyltransferase (ChoAcTase; acetyl-CoA: choline O…
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1978
1978
ACETYL‐CoA SYNTHESIZING ENZYME ACTIVITIES IN SINGLE NERVE CELL BODIES OF RABBIT
H. Hayashi
,
Takahiko Kato
Journal of Neurochemistry
1978
Corpus ID: 41578450
Activities of five enzymes (pyruvate dehydrogenase complex; citrate synthase, EC 4.1.3.7; carnitine acetyltransferase, EC 2.3.1.7…
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1977
1977
Biochemical and histochemical evidence for the existence of a tuberoinfundibular cholinergic pathway in the rat
K. Carson
,
C. Nemeroff
,
+4 authors
J. Kizer
Brain Research
1977
Corpus ID: 35743977
1975
1975
SUBUNITS OF CHOLINE ACETYLTRANSFERASE (EC 2.3.1.6)
L. Chao
Journal of Neurochemistry
1975
Corpus ID: 6020230
Abstract— The molecular weight of choline acetyltransferase is determined to be approx 87,000‐89,000 daltons. There are 808 amino…
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Review
1974
Review
1974
Action mechanism of 2-amino-4-phenylthiazole, a piscine anesthetic, upon the central nervous system of carp.
Y. Sekizawa
,
A. Suzuki
,
K. Tachibana
,
Takahiko Kikuchi
1974
Corpus ID: 85549422
The physio-chemical characteristics of a sedative, 2-amino-4-phenylthiazole, as to its anesthetic properties upon carp (Cyprinus…
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Highly Cited
1973
Highly Cited
1973
KINETICS OF CHOLINE ACETYLTRANSFERASES (EC 2.3.1.6) FROM HUMAN AND OTHER MAMMALIAN CENTRAL AND PERIPHERAL NERVOUS TISSUES
H. White
,
Joyce C. Wu
Journal of Neurochemistry
1973
Corpus ID: 33840813
Abstract— Choline acetyltransferase (EC 2.3.1.6) was partially purified from human caudate nucleus and putamen, human sciatic…
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1961
1961
Effect of Chlorinated Hydrocarbon Insecticides on Insect Choline Acetylase, Condensing Enzyme and Acetylkinase
J. Rothschild
,
G. F. HOWDEN
Nature
1961
Corpus ID: 44532206
THE role of acetylcholine in the transmission of nerve impulses is by no means as well established in insects1,2 as it is in…
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