Chlorobutanol

Known as: 2-Propanol, 2-methyl-1,1,1-trichloro-, 2-Propanol, 1,1,1-trichloro-2-methyl-, Trichlorbutanol 
A colorless to white crystalline compound with a camphoraceous odor and taste. It is a widely used preservative in various pharmaceutical solutions… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
0246819462016

Papers overview

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2004
2004
BACKGROUND AND PURPOSE Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage… (More)
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Highly Cited
2003
Highly Cited
2003
Numerous medications prolong the rate-corrected QT (QTc) interval and induce arrhythmias by blocking ionic current through… (More)
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2001
Highly Cited
2001
PURPOSE To investigate some of the toxicity mechanisms of 10 preservatives currently used in ophthalmic solutions in vitro… (More)
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1996
1996
Although chlorobutanol is available in a large number of preparations, the incidence of toxicity appears to be low. However, with… (More)
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1993
1993
BACKGROUND Although ketamine has been administered spinally in humans, previous neurotoxicity studies have shown that it can… (More)
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1989
1989
By exposing primary cultures of human corneal epithelial cells to a single dose of either benzalkonium chloride or chlorobutanol… (More)
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1989
1989
An in vitro model was used to study the effects of heparinised saline, with or without the preservative chlorbutol, on the… (More)
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Highly Cited
1981
Highly Cited
1981
I have examined the effects of serotonin on the generation of the motor program for swimming by the medicinal leech, Hirudo… (More)
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1975
1975
A fatal chlorobutanol intoxication is reported and a gas chromatographic method for the determination of this drug in human… (More)
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1962
1962
Rats treated with phenobarbitone, phenaglycodol, glutethimide, nikethamide, meprobamate, chlorbutol and chlorpromazine showed an… (More)
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