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Chlorobutanol
Known as:
2-Propanol, 2-methyl-1,1,1-trichloro-
, 2-Propanol, 1,1,1-trichloro-2-methyl-
, Trichlorbutanol
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A colorless to white crystalline compound with a camphoraceous odor and taste. It is a widely used preservative in various pharmaceutical solutions…
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National Institutes of Health
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Related topics
Related topics
34 relations
1 ML Oxytocin 10 UNT/ML Injection
1 ML Oxytocin 10 UNT/ML Injection [Pitocin]
10 ML Novobiocin 40 MG/ML / penicillin G procaine 20000 UNT/ML Prefilled Syringe [Albadry]
Desmopressin Acetate 0.01 MG/ACTUAT Nasal Spray
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Narrower (9)
1-aminoxy-1-chlorobutan-2-ol
4-chloro-1-butanol
Cerumenex
Cerumol
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Broader (1)
Pharmaceutical Preservatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Neurotoxicity of Intra-arterial Papaverine Preserved with Chlorobutanol Used for the Treatment of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Wade S. Smith
,
C. F. Dowd
,
+8 authors
V. Halbach
Stroke
2004
Corpus ID: 330600
Background and Purpose— Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage…
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Review
1999
Review
1999
Bronchoconstrictor additives in bronchodilator solutions.
M. Asmus
,
J. Sherman
,
L. Hendeles
Journal of Allergy and Clinical Immunology
1999
Corpus ID: 594127
Highly Cited
1998
Highly Cited
1998
Effects of Androgen Administration in Men with the AIDS Wasting Syndrome
S. Grinspoon
,
C. Corcoran
,
+9 authors
A. Klibanski
Annals of Internal Medicine
1998
Corpus ID: 21335771
The AIDS wasting syndrome is characterized by loss of lean body mass out of proportion to weight [1, 2]. The few effective…
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Highly Cited
1990
Highly Cited
1990
The Effect of Some Preservatives Used in Nasal Preparations on the Mucus and Ciliary Components of Mucociliary Clearance
A. Batts
,
C. Marriott
,
G. P. Martin
,
C. F. Wood
,
S. W. Bond
The Journal of pharmacy and pharmacology
1990
Corpus ID: 35929179
Abstract— Efficient mucociliary clearance is a function of the physical properties of the mucus coupled to appropriately…
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Highly Cited
1989
Highly Cited
1989
Cytotoxic effects of benzalkonium chloride and chlorobutanol on human corneal epithelial cells in vitro.
B. Tripathi
,
Tripathi Rc
Lens and eye toxicity research
1989
Corpus ID: 34657938
By exposing primary cultures of human corneal epithelial cells to a single dose of either benzalkonium chloride or chlorobutanol…
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Highly Cited
1989
Highly Cited
1989
The Effect of Some Preservatives Used in Nasal Preparations on Mucociliary Clearance
A. Batts
,
Claire Marriott
,
Gary P. Martin
,
S. W. Bond
The Journal of pharmacy and pharmacology
1989
Corpus ID: 23555631
Abstract— The effect of methyl‐ρ‐hydroxybenzoate, propyl‐ρ‐hydroxybenzoate, chlorbutol, chlorocresol, EDTA, benzalkonium chloride…
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Highly Cited
1982
Highly Cited
1982
Detection and identification of volatile organic compounds in blood by headspace gas chromatography as an aid to the diagnosis of solvent abuse.
John D. Ramsey
,
R. Flanagan
Journal of Chromatography A
1982
Corpus ID: 41722505
Highly Cited
1982
Highly Cited
1982
The effects of nasal drops and their additives on human nasal mucociliary clearance.
van de Donk Hj
,
van den Heuvel Ag
,
J. Zuidema
,
Merkus Fw
Rhinology
1982
Corpus ID: 6912970
A method for measurement of nasal mucociliary clearance in vivo is described. A drop, containing saccharine sodium and indigo…
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Highly Cited
1980
Highly Cited
1980
The effects of preservatives on the ciliary beat frequency of chicken embryo tracheas.
van de Donk Hj
,
Muller-Plantema Ip
,
J. Zuidema
,
Merkus Fw
Rhinology
1980
Corpus ID: 38394386
The effects of preservatives on the ciliary beat frequency of chicken embryo tracheas are determined, Polar compounds like…
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Highly Cited
1977
Highly Cited
1977
Loss of antibacterial preservatives from contact lens solutions during storage *
N. E. Richardson
,
D. Davies
,
B. Meakin
,
D. A. Norton
The Journal of pharmacy and pharmacology
1977
Corpus ID: 34132623
The preservative content of 34 commercially available contact lens solutions has been determined. Over half of the solutions…
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