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Chit1 protein, human

Known as: Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase, Chitotriosidase, Methylumbelliferyl-Tetra-N-Acetylchitotetraoside Hydrolase 
Chitotriosidase-1 (466 aa, ~52 kDa) is encoded by the human CHIT1 gene. This protein is involved in the degradation of chitins.
National Institutes of Health

Related topics

Related topics

9 relations
Antimicrobial EffectCHIT1 geneCatabolic ProcessChitinases

Papers overview

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2020
2020
Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion
Objectives The hexanucleotide repeat expansion in the C9orf72 gene is the most common mutation associated with amyotrophic… 
2019
2019
Inflammatory markers in cerebrospinal fluid: independent prognostic biomarkers in amyotrophic lateral sclerosis?
Objective Inflammation is a key pathological hallmark in amyotrophic lateral sclerosis (ALS), which seems to be linked to the… 
2019
2019
Development of Dual Chitinases Inhibitors as Potential New Treatment for Respiratory System Diseases.
Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals and… 
Highly Cited
2013
Highly Cited
2013
Chitotriosidase - a putative biomarker for sporadic amyotrophic lateral sclerosis
BackgroundPotential biomarkers to aid diagnosis and therapy need to be identified for Amyotrophic Lateral Sclerosis, a… 
Highly Cited
2012
Highly Cited
2012
Role of chitotriosidase (chitinase 1) under normal and disease conditions.
Mammalian chitinases belong to the glycosyl hydrolase 18 family based on structural homology and the family includes a large… 
2008
2008
Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates
Background Isocyanates, a leading cause of occupational asthma, are known to induce adaptive immune responses; however, innate… 
2004
2004
Measurement of enzyme kinetics using microscale steady-state kinetic analysis.
This paper describes a new technique--microscale steady-state kinetic analysis (microSKA)--that enables the rapid and parallel… 
Highly Cited
2002
Highly Cited
2002
Expression of hemocyanin and digestive enzyme messenger RNAs in the hepatopancreas of the Black Tiger Shrimp Penaeus monodon.
Highly Cited
2001
Highly Cited
2001
Kinetic properties of chitinase-1 from the fungal pathogen Coccidioides immitis.
The endochitinase from Coccidioides immitis (CiX1) is a member of the class 18 chitinase family. Here we show the enzyme… 
1997
1997
The bifunctional enzyme chitosanase-cellulase produced by the gram-negative microorganism Myxobacter sp. AL-1 is highly similar to Bacillus subtilis endoglucanases
Abstract The gram-negative bacterium Myxobacter sp. AL-1 produces chitosanase-cellulase activity that is maximally excreted… 
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