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Chit1 protein, human

Known as: Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase, Chitotriosidase, Methylumbelliferyl-Tetra-N-Acetylchitotetraoside Hydrolase 
Chitotriosidase-1 (466 aa, ~52 kDa) is encoded by the human CHIT1 gene. This protein is involved in the degradation of chitins.
National Institutes of Health

Papers overview

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2020
2020
Objectives The hexanucleotide repeat expansion in the C9orf72 gene is the most common mutation associated with amyotrophic… 
2019
2019
Objective Inflammation is a key pathological hallmark in amyotrophic lateral sclerosis (ALS), which seems to be linked to the… 
2019
2019
Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals and… 
Highly Cited
2013
Highly Cited
2013
BackgroundPotential biomarkers to aid diagnosis and therapy need to be identified for Amyotrophic Lateral Sclerosis, a… 
Highly Cited
2012
Highly Cited
2012
Mammalian chitinases belong to the glycosyl hydrolase 18 family based on structural homology and the family includes a large… 
2008
2008
Background Isocyanates, a leading cause of occupational asthma, are known to induce adaptive immune responses; however, innate… 
2004
2004
This paper describes a new technique--microscale steady-state kinetic analysis (microSKA)--that enables the rapid and parallel… 
Highly Cited
2002
Highly Cited
2001
Highly Cited
2001
The endochitinase from Coccidioides immitis (CiX1) is a member of the class 18 chitinase family. Here we show the enzyme… 
1997
1997
Abstract The gram-negative bacterium Myxobacter sp. AL-1 produces chitosanase-cellulase activity that is maximally excreted…