FAQ

Chit1 protein, human

Known as: Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase, Chitotriosidase, Methylumbelliferyl-Tetra-N-Acetylchitotetraoside Hydrolase 
Chitotriosidase-1 (466 aa, ~52 kDa) is encoded by the human CHIT1 gene. This protein is involved in the degradation of chitins.

Topic mentions per year

Topic mentions per year

1971-2017
024619712017

Related topics

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11 relations
Antimicrobial EffectCHIT1 geneCatabolic ProcessChitinases
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Broader (1)

chitotriosidase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Chit1 protein, human
macrophage
Hydrolysis
Spleen
Extracellular Space
Chitinases

Papers overview

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2013
2013
Innate Sensing of Chitin and Chitosan
Chitin is the second most common polysaccharide found in nature. It is present in crustacean shells, insect exoskeletons… (More)
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1999
1999
The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences.
Within hours after the ingestion of a blood meal, the mosquito midgut epithelium synthesizes a chitinous sac, the peritrophic… (More)
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1998
1998
Insect resistance of transgenic tobacco expressing an insect chitinase gene
Chitinase expression in the insect gut normally occurs only during moulting, where the chitin of the peritrophic membrane is… (More)
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1995
1995
Molecular cloning and characterization of chitinase genes from Candida albicans.
Chitinase (EC 3.2.1.14) is an important enzyme for the remodeling of chitin in the cell wall of fungi. We have cloned three… (More)
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1995
1995
The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution.
Class II chitinases (EC 3.2.1.14) are plant defense proteins. They hydrolyze chitin, an insoluble beta-1,4-linked polymer of N… (More)
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Highly Cited
1993
Highly Cited
1993
Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.
During development in the mosquito midgut, malarial parasites must traverse a chitin-containing peritrophic matrix (PM) that… (More)
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1993
1993
Detection and quantification of N-acetyl-beta-D-glucosaminidase, chitobiosidase, and endochitinase in solutions and on gels.
Procedures are described for the direct assay of N-acetyl-beta-glucosaminidase (EC 3.2.1.30), chitobiosidase, and endochitinase… (More)
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Highly Cited
1991
Highly Cited
1991
A short C-terminal sequence is necessary and sufficient for the targeting of chitinases to the plant vacuole.
Tobacco contains different isoforms of chitinase (EC 3.2.1.14), a hydrolase thought to be involved in the defense against… (More)
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Highly Cited
1991
Highly Cited
1991
Malaria parasite chitinase and penetration of the mosquito peritrophic membrane.
Malaria parasites (ookinetes) appear to digest the peritrophic membrane in the mosquito midgut during penetration. Previous… (More)
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Highly Cited
1987
Highly Cited
1987
Regulation of a plant pathogenesis-related enzyme: Inhibition of chitinase and chitinase mRNA accumulation in cultured tobacco tissues by auxin and cytokinin.
Two endochitinases (EC 3.2.1.14) of M(r) values of approximately 34,000 and approximately 32,000 have been purified from cultured… (More)
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