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Cathepsins B

Known as: CTSB, APP Secretase, Cathepsin B [Chemical/Ingredient] 
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many… 
National Institutes of Health

Related topics

Related topics

30 relations
APP geneAPP protein, humanAdenocarcinoma Of EsophagusAlzheimer's Disease

Narrower (2)

Ctsb protein, ratprocathepsin B

Broader (1)

caspase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
Highly Cited
1995
Highly Cited
1995
Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures
Highly Cited
1992
Highly Cited
1992
Sequence analysis, tissue distribution, and expression of rat cathepsin S.
Highly Cited
1988
Highly Cited
1988
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B.
A series of peptidyldiazomethanes was synthesized and tested as inactivators of the cysteine proteinases calpain II, cathepsin L… 
Highly Cited
1988
Highly Cited
1988
Amino acid sequences of the human kidney cathepsins H and L
Highly Cited
1985
Highly Cited
1985
Distribution of cathepsins B and H in rat tissues and peripheral blood cells.
The concentrations of cathepsins B and H in various tissues and peripheral blood cells of rats were determined by means of… 
Highly Cited
1982
Highly Cited
1982
The stimulation of protein degradation in muscle by Ca2+ is mediated by prostaglandin E2 and does not require the calcium-activated protease.
Highly Cited
1979
Highly Cited
1979
Crystallization and properties of cathepsin B from rat liver.
Cathepsin B from rat liver was purified to apparent homogeneity by cell-fractionation, freezing and thawing, acetone treatment… 
Review
1978
Review
1978
Muscular dystrophy and activation of proteinases
Evidence is presented for the existence of many different systems of proteolytic enzymes in human skeletal muscle. These include… 
Highly Cited
1974
Highly Cited
1974
Role of individual cathepsins in lysosomal protein digestion as tested by specific inhibitors.
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