Skip to search formSkip to main contentSkip to account menu

Cathepsin-Activatable Cy5 Fluorescent Imaging Probe LUM015

Known as: LUM015 
A cathepsin-activatable fluorescent probe with imaging activity. The cathepsin-activatable fluorescent probe LUM015 contains the Cy5 fluorophore… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer.
We evaluated a cysteine cathepsin-activatable optical imaging probe (LUM015) with improved kinetics relative to larger… 
2018
2018
Intraoperative lumpectomy cavity margin analysis with far-red fluorescence to reduce volume of tissue excised during breast cancer lumpectomy surgery.
e12605Background: Obtaining clear margins in breast cancer lumpectomy surgery is made difficult by complex tumor geometry and… 
2018
2018
Abstract CT166: Expansion into multiple institutions for training in the use of the LUM Imaging System for intraoperative detection of residual cancer in the tumor bed of female subjects with breast…
Background: Standard surgical techniques result in positive lumpectomy margins 20-40% of the time. These positive margins require… 
2016
2016
WE-FG-BRA-11: Theranostic Platinum Nanoparticle for Radiation Sensitization in Breast Cancer Radiotherapy.
PURPOSE We have developed a novel receptor-targeted theranostic platinum nanoparticle (HER-PtNP) for enhanced radiation… 
2014
2014
A phase I study of the safety and activation of a cathepsin-activatable fluorescent cancer-specific probe LUM015.
TPS11135 Background: Local recurrence is a common mode of failure for patients with cancer. Intra-operative detection of… 
2013
2013
A nascent proteome study combining click chemistry with 2DE
To investigate the dynamic cellular response to a condition change, selective labeling of the nascent proteome is necessary. Here… 
2013
2013
Intravital Monitoring of Intact siRNA Using Fluorescence Resonance Energy Transfer
SUMMARY In small interfering RNA (siRNA) therapy, it is necessary to deliver an adequate amount of intact siRNA to the target… 
2008
2008
Gene expression profiling in liver transplant recipients with alcoholic cirrhosis.
2005
2005
Signal Amplification and Increased Sensitivity on Protein Arrays Using 3 DNA Dendrimers
Microarrays spotted with antigens or antibodies have become an important tool for the detection of proteins in a high throughput… 
2002
2002
Ultrasensitive pharmacological characterisation of the voltage-gated potassium channel KV1.3 studied by single-molecule fluorescence microscopy
Abstract. The determination of pharmacologically relevant constants is crucial in order to understand the effects of compounds… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)