Cathepsin-Activatable Cy5 Fluorescent Imaging Probe LUM015
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A first-in-human phase 1 clinical trial of the PEGylated protease-activated fluorescent probe, LUM015, enables tumor imaging at a… Expand Neuroinflammation, mediated by activated microglia and astrocytes, plays a key role in the pathogenesis of many neurological… Expand Cell labeling and tracking are important processes in understanding biologic mechanisms and the therapeutic effect of inoculated… Expand Objective(s): Regulatory T cells, including CD4+CD25+Fox3+ and CD8+CD28- cells play an important role in regulating the balance… Expand Protein carbonyl detection has been commonly used to analyze the degree of damage to proteins under oxidative stress conditions… Expand Manual microscopy is the current reference method for white blood cell (WBC) differential counts. However, manual counts are time… Expand The accurate and sensitive detection of radical oxidants is a central problem in the field of chemical biology. Radical… Expand The direct and noninvasive in vivo visualisation of molecular processes such as ligand–receptor interaction, enzymatic activity… Expand Tumor neovasculature is a potential but, until very recently, unexplored target for boron neutron capture therapy (BNCT) of… Expand Abstract. The determination of pharmacologically relevant constants is crucial in order to understand the effects of compounds… Expand