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Cathepsin-Activatable Cy5 Fluorescent Imaging Probe LUM015

Known as: LUM015 
A cathepsin-activatable fluorescent probe with imaging activity. The cathepsin-activatable fluorescent probe LUM015 contains the Cy5 fluorophore… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
A first-in-human phase 1 clinical trial of the PEGylated protease-activated fluorescent probe, LUM015, enables tumor imaging at a… Expand
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2016
2016
Neuroinflammation, mediated by activated microglia and astrocytes, plays a key role in the pathogenesis of many neurological… Expand
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2014
2014
Cell labeling and tracking are important processes in understanding biologic mechanisms and the therapeutic effect of inoculated… Expand
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2014
2014
Objective(s): Regulatory T cells, including CD4+CD25+Fox3+ and CD8+CD28- cells play an important role in regulating the balance… Expand
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2012
2012
Protein carbonyl detection has been commonly used to analyze the degree of damage to proteins under oxidative stress conditions… Expand
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2010
2010
BACKGROUND Manual microscopy is the current reference method for white blood cell (WBC) differential counts. However, manual… Expand
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2010
2010
The accurate and sensitive detection of radical oxidants is a central problem in the field of chemical biology.[1] Radical… Expand
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2006
2006
The direct and noninvasive in vivo visualisation of molecular processes such as ligand–receptor interaction, enzymatic activity… Expand
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Highly Cited
2005
Highly Cited
2005
Tumor neovasculature is a potential but, until very recently, unexplored target for boron neutron capture therapy (BNCT) of… Expand
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2001
2001
Abstract. The determination of pharmacologically relevant constants is crucial in order to understand the effects of compounds… Expand
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