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Catalytic Domain

Known as: Regions, Catalytic, Core, Catalytic, Catalytic Domains 
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
National Institutes of Health

Related topics

Related topics

2 relations
aspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Emerging views of mitophagy in immunity and autoimmune diseases
ABSTRACT Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating… Expand
Review
2019
Review
2019
PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers
Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination… Expand
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Review
2019
Review
2019
Moving From Poly (ADP-Ribose) Polymerase Inhibition to Targeting DNA Repair and DNA Damage Response in Cancer Therapy.
The DNA damage response (DDR) pathway coordinates the identification, signaling, and repair of DNA damage caused by endogenous or… Expand
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Review
2019
Review
2019
Protein phosphatases in the regulation of mitosis
  • J. Nilsson
  • The Journal of cell biology
  • 2019
    • Corpus ID: 53567190
Nilsson reviews the essential role of phosphoprotein phosphatases in the regulation of controlled dephosphorylation during cell… Expand
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Review
2019
Review
2019
Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.
The anaphase promoting complex/cyclosome (APC/C) E3 ligase controls mitosis and nonmitotic pathways through interactions with… Expand
Review
2018
Review
2018
POLG-related disorders and their neurological manifestations
The POLG gene encodes the mitochondrial DNA polymerase that is responsible for replication of the mitochondrial genome. Mutations… Expand
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Review
2018
Review
2018
Protein Serine/Threonine Phosphatases: Keys to Unlocking Regulators and Substrates.
Protein serine/threonine phosphatases (PPPs) are ancient enzymes, with distinct types conserved across eukaryotic evolution. PPPs… Expand
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Review
2018
Review
2018
Autophagy and innate immunity: Insights from invertebrate model organisms
ABSTRACT Macroautophagy/autophagy is a fundamental intracellular degradation process with multiple roles in immunity, including… Expand
Review
2018
Review
2018
Histone Methyltransferase EZH2: A Therapeutic Target for Ovarian Cancer
Ovarian cancer is the fifth leading cause of cancer-related deaths in females in the United States. There were an estimated 22… Expand
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Review
2018
Review
2018
Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase
Alzheimer´s disease (AD) is a devastating neurodegenerative disease of the elderly population. Genetic evidence strongly suggests… Expand
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