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Catalytic Domain

Known as: Regions, Catalytic, Core, Catalytic, Catalytic Domains 
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
National Institutes of Health

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2 relations
aspects of radiation effectsphysiological aspects

Papers overview

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Review
2016
Review
2016
The amyloid hypothesis of Alzheimer's disease at 25 years
Despite continuing debate about the amyloid β‐protein (or Aβ hypothesis, new lines of evidence from laboratories and clinics… 
Highly Cited
2004
Highly Cited
2004
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell… 
Review
2004
Review
2004
NOX enzymes and the biology of reactive oxygen
  • J. Lambeth
  • Nature Reviews Immunology
  • 2004
  • Corpus ID: 24384987
Professional phagocytes generate high levels of reactive oxygen species (ROS) using a superoxide-generating NADPH oxidase as part… 
Highly Cited
2004
Highly Cited
2004
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of tissues during ageing in humans, monkeys… 
Highly Cited
2001
Highly Cited
2001
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
Review
2000
Review
2000
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.
NF-kappaB (nuclear factor-kappaB) is a collective name for inducible dimeric transcription factors composed of members of the Rel… 
Review
1999
Review
1999
CDK inhibitors: positive and negative regulators of G1-phase progression.
Mitogen-dependent progression through the first gap phase (G1) and initiation of DNA synthesis (S phase) during the mammalian… 
Review
1995
Review
1995
The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1
  • S. Hanks, T. Hunter
  • FASEB journal : official publication of the…
  • 1995
  • Corpus ID: 21377422
The eukaryotic protein kinases make up a large superfamily of homologous proteins. They are related by virtue of their kinase… 
Review
1989
Review
1989
The structure and regulation of protein phosphatases.
  • P. Cohen
  • Annual review of biochemistry
  • 1989
  • Corpus ID: 29930846
Four major serine/threonine-specific protein phosphatase catalytic subunits are present in the cytoplasm of animal cells. Three… 
Review
1988
Review
1988
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
In recent years, members of the protein kinase family have been discovered at an accelerated pace. Most were first described, not… 
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