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Catalytic Domain
Known as:
Regions, Catalytic
, Core, Catalytic
, Catalytic Domains
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The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
National Institutes of Health
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Related topics
Related topics
2 relations
aspects of radiation effects
physiological aspects
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
The amyloid hypothesis of Alzheimer's disease at 25 years
D. Selkoe
,
J. Hardy
EMBO molecular medicine
2016
Corpus ID: 10098926
Despite continuing debate about the amyloid β‐protein (or Aβ hypothesis, new lines of evidence from laboratories and clinics…
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Highly Cited
2004
Highly Cited
2004
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
Y. Samuels
,
Zhenghe Wang
,
+12 authors
V. Velculescu
Science
2004
Corpus ID: 10147415
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell…
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Review
2004
Review
2004
NOX enzymes and the biology of reactive oxygen
J. Lambeth
Nature Reviews Immunology
2004
Corpus ID: 24384987
Professional phagocytes generate high levels of reactive oxygen species (ROS) using a superoxide-generating NADPH oxidase as part…
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Highly Cited
2004
Highly Cited
2004
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A. Trifunovic
,
A. Wredenberg
,
+10 authors
N. Larsson
Nature
2004
Corpus ID: 4327793
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of tissues during ageing in humans, monkeys…
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Highly Cited
2001
Highly Cited
2001
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
A. C. Epstein
,
J. Gleadle
,
+17 authors
P. Ratcliffe
Cell
2001
Corpus ID: 18372306
Review
2000
Review
2000
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.
M. Karin
,
Y. Ben-Neriah
Annual review of immunology
2000
Corpus ID: 23525297
NF-kappaB (nuclear factor-kappaB) is a collective name for inducible dimeric transcription factors composed of members of the Rel…
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Review
1999
Review
1999
CDK inhibitors: positive and negative regulators of G1-phase progression.
C. Sherr
,
J. Roberts
Genes & development
1999
Corpus ID: 31948941
Mitogen-dependent progression through the first gap phase (G1) and initiation of DNA synthesis (S phase) during the mammalian…
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Review
1995
Review
1995
The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1
S. Hanks
,
T. Hunter
FASEB journal : official publication of the…
1995
Corpus ID: 21377422
The eukaryotic protein kinases make up a large superfamily of homologous proteins. They are related by virtue of their kinase…
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Review
1989
Review
1989
The structure and regulation of protein phosphatases.
P. Cohen
Annual review of biochemistry
1989
Corpus ID: 29930846
Four major serine/threonine-specific protein phosphatase catalytic subunits are present in the cytoplasm of animal cells. Three…
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Review
1988
Review
1988
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
S. Hanks
,
A. M. Quinn
,
T. Hunter
Science
1988
Corpus ID: 22597094
In recent years, members of the protein kinase family have been discovered at an accelerated pace. Most were first described, not…
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