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Caspases, Effector

Known as: Caspases, Effector [Chemical/Ingredient], Effector Caspases 
A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic action of INITIATOR CASPASES. Once activated they… 
National Institutes of Health

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In BloodProcess of secretionaspects of radiation effectschemical synthesis

Papers overview

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Review
2008
Review
2008
microRNAs and death receptors.
Highly Cited
2008
Highly Cited
2008
Radiosensitizing effects of plumbagin in cervical cancer cells is through modulation of apoptotic pathway
Radiotherapy is the primary line of cancer treatment for cervical cancer and is known to induce cell death in tumors… 
2008
2008
N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine
Cyclin-dependent kinases (CDKs) and their regulators show frequent abnormalities in tumors. Ten low molecular weight… 
2007
2007
Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus.
Review
2006
Review
2006
Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model.
2006
2006
Extensive regions of the FADD death domain are required for binding to the TRAIL receptor DR5
Extensive regions of the FADD death domain are required for binding to the TRAIL receptor DR5 
2005
2005
Caspase-9 and effector caspases have sequential and distinct effects on mitochondria
Proapoptotic Bcl-2 family members alter mitochondrial permeability resulting in the release of apoptogenic factors that initiate… 
2003
2003
Caspase regulation of genotoxin‐induced neural precursor cell death
Neural precursor cells (NPCs) critically regulate brain morphogenesis and recent studies have revealed an unexpectedly high… 
2001
2001
Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies.
Highly Cited
1999
Highly Cited
1999
Mitochondria connects the antigen receptor to effector caspases during B cell receptor-induced apoptosis in normal human B cells.
We have previously reported that CD40 stimulation sensitizes human memory B cells to undergo apoptosis upon subsequent B cell… 
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