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Cancer/Testis Antigen 2

Known as: LAGE-1, Autoimmunogenic Cancer/Testis Antigen NY-ESO-2, CT6.2 
Cancer/testis antigen 2 (210 aa, ~21 kDa) is encoded by the human CTAG2 gene. This protein may play a role in tumorigenesis of several tissues.
National Institutes of Health

Related topics

Related topics

4 relations
CTAG2 geneCancer Promoting GenesMetastasis InductionNeoplastic Cell Transformation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Expression of cancer–testis antigens in esophageal cancer and their progress in immunotherapy
PurposeEsophageal cancer is a common disease in China with low survival rate due to no obvious early symptoms and lack of… 
2017
2017
A pilot study of peripheral blood BDCA-1 (CD1c) positive dendritic cells pulsed with NY-ESO-1 ISCOMATRIX™ adjuvant.
AIM Pilot clinical trial of NY-ESO-1 (ESO) protein in ISCOMATRIX™ adjuvant pulsed onto peripheral blood dendritic cells (PBDC… 
2012
2012
Pattern of cancer/testis antigen expression in lung cancer patients
Cancer/testis (CT) antigens represent promising targets for immunotherapy. We investigated the composite expression of 13 CT… 
2012
2012
Adoptive Transfer of Gene-Modified T-Cells Engineered to Express High-Affinity TCRs for Cancer-Testis Antigens (CTAs) NY-ESO-1 or Lage-1, in MM Patients Post Auto-SCT
Abstract 472 Background: Despite recent therapeutic advances, multiple myeloma (MM) remains primarily an incurable cancer… 
Highly Cited
2007
Highly Cited
2007
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.
This study aims to analyze the expression of 14 cancer/testis (CT) antigens in multiple myeloma (MM) to identify possible… 
Highly Cited
2004
Highly Cited
2004
Immunohistochemical and Molecular Analysis of Human Melanomas for Expression of the Human Cancer-Testis Antigens NY-ESO-1 and LAGE-1
Purpose: NY-ESO-1 and LAGE-1 are homologous cancer-testis antigens, which are expressed in many different cancers. It is… 
Highly Cited
2004
Highly Cited
2004
Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display
Serological cloning of tumor-associated antigens (TAAs) using patient autoantibodies and tumor cDNA expression libraries (SEREX… 
2004
2004
[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery].
OBJECTIVE To investigate the possibility of utilizing cancer-testi (CT) antigens as targets for immunotherapy of non-small cell… 
Review
2002
Review
2002
Towards Defining Specific Antigens for Cutaneous Lymphomas
Cutaneous lymphomas (CLs) are a heterogeneous group of malignancies of T-cell (cutaneous T-cell lymphoma, CTCL) or B-cell… 
Highly Cited
2001
Highly Cited
2001
Expression of multiple cancer-testis antigen genes in gastrointestinal and breast carcinomas
Cancer-testis antigens (CTAs) such as MAGE are selectively expressed in various types of human neoplasms but not in normal… 
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