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Cancer Stem Cells
Known as:
Stem Cell, Cancer
, Cell, Cancer Stem
, Cells, Cancer Stem
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A malignant cell which may derive from mutations in normal stem cells. Cancer stem cells proliferate and give rise to other malignant cells. They may…
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Neoplastic Stem Cells
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Breast cancer stem cells
T. Owens
,
M. Naylor
Frontiers in Physiology
2013
Corpus ID: 15111269
Cancer metastasis, resistance to therapies and disease recurrence are significant hurdles to successful treatment of breast…
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Review
2013
Review
2013
Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization
V. Tirino
,
V. Desiderio
,
+6 authors
G. Papaccio
The FASEB Journal
2013
Corpus ID: 31303141
Primary tumors are responsible for 10% of cancer deaths. In most cases, the main cause of mortality is the formation of…
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Review
2011
Review
2011
Cancer stem cell niche: the place to be.
Tijana Borovski
,
F. de Sousa e Melo
,
L. Vermeulen
,
J. Medema
Cancer Research
2011
Corpus ID: 15654783
Tumors are being increasingly perceived as abnormal organs that, in many respects, recapitulate the outgrowth and differentiation…
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Review
2011
Review
2011
Aldehyde dehydrogenase: Its role as a cancer stem cell marker comes down to the specific isoform
P. Marcato
,
C. Dean
,
C. Giacomantonio
,
Patrick Lee
Cell Cycle
2011
Corpus ID: 37368096
Recent evidence suggests that enhanced aldehyde dehydrogenase (ALDH) activity is a hallmark of cancer stem cells (CSC) measurable…
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Review
2011
Review
2011
MicroRNA regulation of cancer stem cells.
Can Liu
,
D. Tang
Cancer Research
2011
Corpus ID: 6554842
Cancer stem cells (CSC), or cancer cells with stem cell properties, have been reported in many human tumors and are thought to be…
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Highly Cited
2010
Highly Cited
2010
Inhibition of Notch Signaling in Glioblastoma Targets Cancer Stem Cells via an Endothelial Cell Intermediate
K. Hovinga
,
F. Shimizu
,
+8 authors
V. Tabar
Stem Cells
2010
Corpus ID: 40435299
Glioblastoma multiforme (GBM) is a highly heterogeneous malignant tumor. Recent data suggests the presence of a hierarchical…
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Highly Cited
2009
Highly Cited
2009
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
Alysha K Croker
,
David Goodale
,
+4 authors
A. Allan
Journal of Cellular and Molecular Medicine
2009
Corpus ID: 20202125
Cancer stem cells (CSCs) have recently been identified in leukaemia and solid tumours; however, the role of CSCs in metastasis…
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Highly Cited
2009
Highly Cited
2009
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance
A. Alvero
,
R. Chen
,
+8 authors
G. Mor
Cell Cycle
2009
Corpus ID: 25959056
A major burden in the treatment of ovarian cancer is the high percentage of recurrence and chemoresistance. Cancer stem cells…
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Highly Cited
2008
Highly Cited
2008
Cancer stem cells: a step toward the cure.
B. Boman
,
M. Wicha
Journal of Clinical Oncology
2008
Corpus ID: 28125683
This special issue of Journal of Clinical Oncology is devoted to the emerging field of cancer stem cells (CSCs). The goal of this…
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Review
2006
Review
2006
The cancer stem cell hypothesis: a work in progress
Brent Tan
,
Christopher Y. Park
,
L. Ailles
,
I. Weissman
Laboratory Investigation
2006
Corpus ID: 29322021
There is a growing body of evidence that supports the idea that malignant tumors are initiated and maintained by a population of…
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