FAQ

Cancer-Associated Fibroblasts

Known as: Fibroblast, Cancer-Associated, Fibroblasts, Cancer-Associated, Cancer-Associated Fibroblast 
Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
0204020072017

Related topics

Related topics

4 relations
MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Cancer-Associated Fibroblasts
physiological aspects
Microbiological
Process of secretion
aspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Osteopontin Mediates an MZF1-TGF-β1-Dependent Transformation of Mesenchymal Stem Cells into Cancer Associated Fibroblasts in Breast Cancer
Interactions between tumor cells and cancer-associated fibroblasts (CAFs) in the tumor microenvironment significantly influence… (More)
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Review
2015
Review
2015
Cancer-Associated Fibroblasts Connect Metastasis-Promoting Communication in Colorectal Cancer
Colorectal cancer (CRC) progression and eventually metastasis is directed in many aspects by a circuitous ecosystem consisting of… (More)
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2013
2013
Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells
Endometrial cancer is the most commonly diagnosed gynecologic malignancy worldwide; yet the tumor microenvironment, especially… (More)
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Highly Cited
2012
Highly Cited
2012
Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts
BACKGROUND Bisphenol A (BPA) is the principal constituent of baby bottles, reusable water bottles, metal cans, and plastic food… (More)
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Highly Cited
2011
Highly Cited
2011
Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis
It has been well documented that microenvironment consisting of stroma affects breast cancer progression. However, the mechanisms… (More)
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Highly Cited
2010
Highly Cited
2010
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.
Cancer-associated fibroblasts (CAFs) support tumorigenesis by stimulating angiogenesis, cancer cell proliferation, and invasion… (More)
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Highly Cited
2010
Highly Cited
2010
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-B-Dependent Manner
Neta Erez,1,2,3 Morgan Truitt,1,2,3 Peter Olson,1,2,3 and Douglas Hanahan1,2,3,4,* 1Helen Diller Family Comprehensive Cancer… (More)
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Highly Cited
2009
Highly Cited
2009
Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression
BACKGROUND Tumor associated fibroblasts (TAF), are essential for tumor progression providing both a functional and structural… (More)
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Highly Cited
2009
Highly Cited
2009
Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model
BACKGROUND Local inflammation associated with solid tumors commonly results from factors released by tumor cells and the tumor… (More)
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2008
2008
Identification of Molecular Distinctions Between Normal Breast-Associated Fibroblasts and Breast Cancer-Associated Fibroblasts
Stromal fibroblasts influence the behavior of breast epithelial cells. Fibroblasts derived from normal breast (NAF) inhibit… (More)
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