Skip to search formSkip to main contentSkip to account menu

Canavan Disease

Known as: Disease, Canavan, Leukodystrophy, Spongiform, ASPA DEFICIENCY 
A rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Preamble Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific… 
Highly Cited
2012
Highly Cited
2012
Gene therapy for Canavan disease results in a decrease in pathologically elevated N-acetyl-aspartate concentrations in the brain… 
Highly Cited
2006
Highly Cited
2006
Canavan disease is a rare leukodystrophy with no current treatment. rAAV‐ASPA has been developed for gene delivery to the central… 
Highly Cited
2002
Highly Cited
2002
This clinical protocol describes virus-based gene transfer for Canavan disease, a childhood leukodystrophy. Canavan disease, also… 
Review
1995
Review
1995
Highly Cited
1993
Highly Cited
1993
Canavan disease, an autosomal recessive leukodystrophy, is caused by deficiency of aspartoacylase and accumulation of N… 
Review
1991
Review
1991
  • B. Miller
  • NMR in biomedicine
  • 1991
  • Corpus ID: 8843464
The structure and function of the chemicals contributing to the three main peaks seen with 1H NMR spectroscopy, N‐acetyl‐L…