Calpain-1 Cell Spread Pathway

Known as: mu-Calpain Cell Spread Pathway, uCalpain and friends in Cell spread 
The mammalian calpain gene family currently contains 13 distinct large subunit products most of which complex with one of two smaller 30kDa subunits… (More)
National Institutes of Health

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CAPN1 protein, humanCAPN1 wt AllelePTK2 protein, humanPTK2 wt Allele
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Papers overview

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2018
2018
Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain
Autoproteolysis of human erythrocyte calpain-1 proceeds in vitro at high [Ca2+], through the conversion of the 80-kDa catalytic… (More)
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Review
2008
Review
2008
Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics.
Glaucoma is a group of irreversible blinding eye diseases affecting over 70 million people worldwide. Systemic delivery of… (More)
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