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Calcium Release Activated Calcium Channels

Known as: Calcium Release-Activated Channels, Calcium Release Activated Calcium Channels [Chemical/Ingredient], Calcium Release Activated Channels 
Specialized calcium channels that localize to the ENDOPLAMSIC RETICULUM and PLASMA MEMBRANE. They contain the pore subunit ORAI1 PROTEIN which is… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2018
2018
Phosphorylation-mediated structural changes within the SOAR domain of stromal interaction molecule 1 enable specific activation of distinct Orai channels.
Low-conductance, highly calcium-selective channels formed by the Orai proteins exist as store-operated CRAC channels and store… 
2016
2016
Exploiting the role of various types of ion-channels against chemically induced inflammatory bowel disease in male Wistar rats
Review
2009
Review
2009
Roles of Cav channels and AHNAK1 in T cells: the beauty and the beast
Summary:  T lymphocytes require Ca2+ entry though the plasma membrane for their activation and function. Recently, several routes… 
2008
2008
Subunit stoichiometry and channel pore structure of ion channels: all for one, or one for one?
Ion channels are macromolecular protein complexes that open and close their pores to control rapid ion fluxes across the cell… 
Review
2008
Review
2008
Store‐operated channels: mechanisms and function
For many years, how Ca2+ entered non-excitable cells remained enigmatic. There was a suspicion that Ca2+ channels were involved… 
2007
2007
MODULACIÓN LOCAL DE UN CANAL OPERADO POR DEPÓSITO
In T lymphocytes, the Ca2+ entry mainly occurs through a particular type of store-operated Ca2+ (SOC) channel known as ICRAC… 
Review
2006
Review
2006
Roles of CRAC and Cav-like channels in T cells: more than one gatekeeper?
2006
2006
Lokalisation des humanen Ionenkanals TRPM4 und seine Bedeutung für Membranpotential und Ca2+-Signale
TRPM2 und TRPM4 sind Mitglieder der Melastatin-Familie der TRP-Ionenkanale. Fur das humane TRPM4-Gen wurden mehrere alternative… 
2003
2003
Effects of Large Clostridial Cytotoxins on Activation of RBL 2H3-hm1 Mast Cells Indicate Common and Different Roles of Rac in FcεRI and M1-Receptor Signaling
Using Rho GTPases-inhibiting clostridial cytotoxins, we showed recently in RBL cells that the GTPase Rac is involved in FcεRI… 
Review
1998
Review
1998
G protein signalling pathways in myometrium: affecting the balance between contraction and relaxation.
Heterotrimeric G proteins are actively involved in intracellular signalling in the myometrium and play important roles in… 
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