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Protein splicing is a self-catalyzed and spontaneous post-translational process in which inteins excise themselves out of… Expand The molecular details of how copper (Cu) is transferred from the human Cu chaperone Atox1 to metal-binding domains (MBDs) of P(1B… Expand To elucidate the molecular pathways that modulate renal cyst growth in ADPKD, we performed global gene profiling on cysts of… Expand As an intermediate filament (IF)-based cytolinker protein, plectin plays a key role in the maintenance of cellular… Expand Wild-type syndet is efficiently recruited at the plasma membrane in transfected AtT-20 cells. A deletion at the cysteine-rich… Expand The actions of insulin-like growth factors (IGFs) are modulated by a family of six high affinity binding proteins (IGFBPs 1–6… Expand BACKGROUND
Amidotransferases use the amide nitrogen of glutamine in a number of important biosynthetic reactions. They are… Expand Glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase from Escherichia coli exhibits a basal PRPP-independent glutaminase… Expand A family of four glutamine amidotransferases has a homologous glutamine amide transfer domain, designated purF-type, that is… Expand Specific chemical modifications of apamin have been used to study the residues involved in its toxic action. Transformation of… Expand