FAQ

CYP4F3 gene

Known as: LTB4 OMEGA-HYDROXYLASE, CYP4F3, LTB4H 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
01219992017

Related topics

Related topics

1 relation
leukotriene B4 20-hydroxylase

Related mentions per year

Related mentions per year

1999-2017
1990200020102020
CYP4F3 gene
leukotriene B4 20-hydroxylase

Papers overview

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2013
2013
Mass spectrometry-based proteomic analysis of human liver cytochrome(s) P450.
The major objective of personalized medicine is to select optimized drug therapies and to a large degree such mission is… (More)
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2012
2012
Statins increase cytochrome P450 4F3-mediated eicosanoids production in human liver cells: a PXR dependent mechanism.
In the present study, the ability of lovastatin, a competitive inhibitor of HMG-CoA reductase, to regulate the gene expression… (More)
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2009
2009
Induction of CYP4F3 by benzene metabolites in human white blood cells in vivo in human promyelocytic leukemic cell lines and ex vivo in human blood neutrophils.
Exposure to benzene elicits a spectrum of hematotoxicity ranging from reduction of peripheral blood cell counts to aplastic… (More)
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2008
2008
Distinction between human cytochrome P450 (CYP) isoforms and identification of new phosphorylation sites by mass spectrometry.
In mammals, Cytochrome P450 (CYP) enzymes are bound to membranes of the endoplasmic reticulum and mitochondria, where they are… (More)
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2006
2006
A functional candidate screen for coeliac disease genes
It is increasingly evident that different inflammatory disorders show some overlap in their pathological features, concurrence in… (More)
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2004
2004
Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.
CYP4F isoforms are involved in the oxidation of important cellular mediators such as leukotriene B4 (LTB4) and prostaglandins… (More)
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Review
2002
Review
2002
Prostaglandin and leukotriene omega-hydroxylases.
Omega and subterminal hydroxylations of prostaglandins (PGs), leukotriene B4 (LTB4) and some related eicosanoids are catalyzed by… (More)
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2001
2001
A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine.
Small intestinal microsomes of cynomolgus monkeys were found to catalyze hydroxylation and dealkylation of an H(1)-antihistamine… (More)
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2001
2001
Covalent linkage of prosthetic heme to CYP4 family P450 enzymes.
An extensive body of research on the structural properties of cytochrome P450 enzymes has established that these proteins possess… (More)
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1999
1999
Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles.
19R-Hydroxyprostaglandins are major components of human seminal fluid. They are apparently formed in the seminal vesicles by… (More)
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