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CYP4F3 gene

Known as: LTB4 OMEGA-HYDROXYLASE, CYP4F3, LTB4H 
National Institutes of Health

Related topics

Related topics

1 relation
leukotriene B4 20-hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Discovery of rubiarbonone C as a selective inhibitor of cytochrome P450 4F enzymes
Cytochrome P450 (CYP) enzymes, particularly CYP4A/4F, are the major ω-hydroxylases of arachidonic acid (AA) that can produce 20… 
2017
2017
Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes—A Link in the Onset and Development of Cardiovascular Disease?
Arachidonic acid can be metabolized by cytochrome P450 (CYP450) enzymes in a tissue- and cell-specific manner to generate… 
2013
2013
Differential Expression of Cytochrome P450 Omega-hydroxylase Isoforms and Their Association with Clinicopathological Features in Pancreatic Ductal Adenocarcinoma
BackgroundThe cytochrome P450 (CYP) superfamily consists of enzymes that catalyze the oxidation of lipids, steroids, and drugs… 
2006
2006
A functional candidate screen for coeliac disease genes
It is increasingly evident that different inflammatory disorders show some overlap in their pathological features, concurrence in… 
Highly Cited
2002
Highly Cited
2002
Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.
The cytochromes P450 belong to a superfamily of enzymes involved in a diverse array of endobiotic and xenobiotic metabolic… 
Review
2002
Review
2002
Prostaglandin and leukotriene omega-hydroxylases.
Omega and subterminal hydroxylations of prostaglandins (PGs), leukotriene B4 (LTB4) and some related eicosanoids are catalyzed by… 
Highly Cited
2002
Highly Cited
2002
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.
The purpose of the study was to elucidate human intestinal cytochrome P450 isoform(s) involved in the metabolism of an… 
Highly Cited
2001
Highly Cited
2001
Covalent linkage of prosthetic heme to CYP4 family P450 enzymes.
An extensive body of research on the structural properties of cytochrome P450 enzymes has established that these proteins possess… 
2001
2001
Involvement of CYP 2 J 2 and CYP 4 F 12 in the Metabolism of Ebastine in Human Intestinal Microsomes
The purpose of the study was to elucidate human intestinal cytochrome P450 isoform(s) involved in the metabolism of an… 
Highly Cited
1999
Highly Cited
1999
Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles.
19R-Hydroxyprostaglandins are major components of human seminal fluid. They are apparently formed in the seminal vesicles by… 
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