A functional candidate screen for coeliac disease genes

@article{Curley2006AFC,
  title={A functional candidate screen for coeliac disease genes},
  author={Christine R Curley and Alienke J. Monsuur and Martin C. Wapenaar and John D Rioux and Cisca Wijmenga},
  journal={European Journal of Human Genetics},
  year={2006},
  volume={14},
  pages={1215-1222}
}
It is increasingly evident that different inflammatory disorders show some overlap in their pathological features, concurrence in families and individuals, and shared genetic factors. This might also be true for coeliac disease, a chronic inflammatory disorder of the gastrointestinal system, which shares two linkage regions with inflammatory bowel disease: on chromosome 5q31 (CELIAC2 and IBD5) and 19p13 (CELIAC4 and IBD6). We hypothesised that these regions contain genes that contribute to… CONTINUE READING