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CYP2W1 gene

Known as: CYP2W1, FLJ20359, CYTOCHROME P450, FAMILY 2, SUBFAMILY W, POLYPEPTIDE 1 
National Institutes of Health

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Cytochrome P450

Papers overview

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2016
2016
Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
CYP2W1 is a recently discovered human cytochrome P450 enzyme with a distinctive tumor-specific expression pattern. We show here… 
2016
2016
Abstract 3105: Probing cytochrome P450 activity with benzofuran-based duocarmycins in a panel of head and neck cancer cell lines and CYP1A1, 1B1 and CYP2W1 transfected cell lines
Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA Background: The cytochrome P450 (CYP) isoforms… 
2015
2015
Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT…
Abstract 1. Ethanol consumption and smoking alter the expression of certain drug-metabolizing enzymes and transporters… 
2014
2014
289 Progress in drugging CYP1A1, 1B1 and CYP2W1 overexpressed in cancer
2013
2013
Abstract 2224: Re-engineering of the duocarmycin structural architecture enables tumour-selective CYP2W1-mediated drug activation in human colon cancer xenografts.
There is now growing evidence that CYP1A1, 1B1, 2J2, 2S1 and 2W1 are over-expressed in many human tumour types. The ultrapotent… 
2013
2013
Kirurgi CYP 2 W 1 in colorectal cancer – aspects of risk , prognosis and future treatment options
Colorectal cancer (CRC) is a common disease and a major cause of cancer related death globally. Prognosis is rather good in early… 
2012
2012
CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interaction of CYP2W1 genotypes with risk factors in Mexican women with breast cancer.
Breast cancer (BCa) is the leading type of cancer in Mexican women. Genetic factors, such as single nucleotide polymorphisms (SNP… 
2011
2011
Preclinical Development CYP 2 S 1 and CYP 2 W 1 Mediate 2-( 3 , 4-Dimethoxyphenyl )-5-Fluorobenzothiazole ( GW-610 , NSC 721648 ) Sensitivity in Breast and Colorectal Cancer Cells
Both 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203; NSC 703786) and 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW… 
2008
2008
Genetic Polymorphisms and Haplotype Structures of the Human CYP2W1 Gene in a Japanese Population
A novel human cytochrome P450, designated CYP2W1, has recently been identified and is found to be present mainly in tumor cells… 
2008
2008
Epigenic regulation and posttranslational modification of human cytochrome P450s : Focus on CYP2W1, CYP1A2 and CYP2C18
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