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CYP2E1 wt Allele

Known as: P450C2E, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 wt Allele, CYP2E 
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
In many liver disorders, oxidative stress-related inflammation and apoptosis are important pathogenic components, finally… Expand
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2012
2012
Cytochromes P450 (P450s) are a superfamily of enzymes that have critical functions in liver to catalyze the biotransformation of… Expand
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Review
2008
Review
2008
Heart failure is a very serious cardiovascular disease that affects more than five million people in North America. The role of… Expand
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Highly Cited
2004
Highly Cited
2004
1. The metabolism by HepG2 cell from two sources (M1, M2) of 12 substrates is reported: ethoxyresorufin, ethoxycoumarin… Expand
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Highly Cited
2003
Highly Cited
2003
Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE This research investigated the biotransformation of thalidomide by cytochrome P-450 (CYP). EXPERIMENTAL DESIGN We used… Expand
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Highly Cited
2000
Highly Cited
2000
We studied the long-term effects of streptozotocin-induced diabetes on tissue-specific cytochrome P450 (CYP) and glutathione… Expand
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Highly Cited
2000
Highly Cited
2000
Epoxyeicosatrienoic acids (EETs) are major products of cytochrome P450 (CYP)-catalyzed metabolism of arachidonic acid in the… Expand
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2000
2000
Little information is available regarding the vasoactive effects of epoxyeicosatrienoic acids (EETs) in the lung. We demonstrate… Expand
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Highly Cited
1988
Highly Cited
1988
The human P450IIE1 gene, coding for an ethanol-inducible nitrosamine-metabolizing P-450, was isolated from a lambda EMBL3 genomic… Expand
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