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CYP2E1 wt Allele

Known as: P450C2E, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 wt Allele, CYP2E 
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1… 
National Institutes of Health

Related topics

Related topics

17 relations
Arachidonic Acid Metabolism PathwayCarcinogen MetabolismCarcinoma of lungCytochrome P-450 CYP2E1

Broader (1)

CYP2E1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Current Trends in Biotechnology and Pharmacy
Multianalyte immunoassay has gained increasing attention due to its high sample throughput, short assay time, low sample… 
Highly Cited
2010
Highly Cited
2010
Effect of Regular Organic Solvents on Cytochrome P450-Mediated Metabolic Activities in Rat Liver Microsomes
The effects of regular organic solvents on the metabolic activities of various human cytochromes P450 (P450s) have been reported… 
Review
2010
Review
2010
Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
This study aimed to investigate the biotransformation of cat liver microsomes in comparison to dogs and humans using a high… 
2002
2002
Inhibition of CYP3A‐mediated oxidation in human hepatic microsomes by the dietary derived complex phenol, gallic acid
Plant polyphenols, such as gallic acid, have been reported to have a range of biological activities including antimutagenic… 
Highly Cited
2000
Highly Cited
2000
Hepatic and central nervous system cytochrome P450 are down-regulated during lipopolysaccharide-evoked localized inflammation in brain.
The effect of central nervous system inflammation on the levels and activity of hepatic and brain cytochrome P450 were examined… 
Highly Cited
1999
Highly Cited
1999
Effect of leptin on cytochrome P-450, conjugation, and antioxidant enzymes in the ob/ob mouse.
Leptin is a hormone that is secreted by adipocytes and regulates body weight through its effect on satiety and energy metabolism… 
Review
1998
Review
1998
Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.
Highly Cited
1997
Highly Cited
1997
Role of CYP3A in ethanol-mediated increases in acetaminophen hepatotoxicity.
CYP2E is considered the only form of cytochrome P450 responsible for ethanol-mediated increases in acetaminophen hepatotoxicity… 
Highly Cited
1995
Highly Cited
1995
Characterization of metallothionein-I-transgenic mice.
A metallothionein-I-transgenic mouse strain (MT-TG) was characterized to determine whether they would be suitable to study the… 
1995
1995
Defective expression of cytochrome P450 proteins in the liver of the genetically obese Zucker rat.
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