Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CYP2E1 wt Allele

Known as: P450C2E, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 wt Allele, CYP2E 
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
In many liver disorders, oxidative stress-related inflammation and apoptosis are important pathogenic components, finally… Expand
Highly Cited
2011
Highly Cited
2011
The cytochrome P450 (P450) family of enzymes is a major player in the metabolism of therapeutic drugs available on the market… Expand
  • figure 1
  • figure 2
  • table 2
  • table 3
  • figure 3
Review
2008
Review
2008
Heart failure is a very serious cardiovascular disease that affects more than five million people in North America. The role of… Expand
Highly Cited
2004
Highly Cited
2004
  • N. Hewitt, P. Hewitt
  • Xenobiotica; the fate of foreign compounds in…
  • 2004
  • Corpus ID: 25129443
1. The metabolism by HepG2 cell from two sources (M1, M2) of 12 substrates is reported: ethoxyresorufin, ethoxycoumarin… Expand
Highly Cited
2003
Highly Cited
2003
Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2002
Highly Cited
2002
PURPOSE This research investigated the biotransformation of thalidomide by cytochrome P-450 (CYP). EXPERIMENTAL DESIGN We used… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Highly Cited
2001
Highly Cited
2001
We have investigated the effect of herbal teas (peppermint, chamomile and dandelion) on the activity of hepatic phase I and phase… Expand
Highly Cited
2000
Highly Cited
2000
We studied the long‐term effects of streptozotocin‐induced diabetes on tissue‐specific cytochrome P450 (CYP) and glutathione… Expand
Highly Cited
1990
Highly Cited
1990
 
Highly Cited
1988
Highly Cited
1988
The human P450IIE1 gene, coding for an ethanol-inducible nitrosamine-metabolizing P-450, was isolated from a lambda EMBL3 genomic… Expand