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CYP2E1 wt Allele

Known as: P450C2E, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 wt Allele, CYP2E 
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1… 
National Institutes of Health

Related topics

Related topics

17 relations
Arachidonic Acid Metabolism PathwayCarcinogen MetabolismCarcinoma of lungCytochrome P-450 CYP2E1

Broader (1)

CYP2E1 gene

Papers overview

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Highly Cited
2017
Highly Cited
2017
Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue*
The lack of high-throughput methods to analyze the adipose tissue protein composition limits our understanding of the protein… 
Highly Cited
2016
Highly Cited
2016
Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related signaling.
Review
2008
Review
2008
Examining tree canopy models for CFD prediction of wind environment at pedestrian level
Highly Cited
2004
Highly Cited
2004
Phase I and II enzyme characterization of two sources of HepG2 cell lines
  • N. HewittP. Hewitt
  • Xenobiotica; the fate of foreign compounds in…
  • 2004
  • Corpus ID: 25129443
1. The metabolism by HepG2 cell from two sources (M1, M2) of 12 substrates is reported: ethoxyresorufin, ethoxycoumarin… 
Highly Cited
2003
Highly Cited
2003
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.
Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450… 
Highly Cited
2002
Highly Cited
2002
Thalidomide metabolism by the CYP2C subfamily.
PURPOSE This research investigated the biotransformation of thalidomide by cytochrome P-450 (CYP). EXPERIMENTAL DESIGN We used… 
Highly Cited
2001
Highly Cited
2001
Effect of herbal teas on hepatic drug metabolizing enzymes in rats
We have investigated the effect of herbal teas (peppermint, chamomile and dandelion) on the activity of hepatic phase I and phase… 
Highly Cited
2000
Highly Cited
2000
Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin‐induced diabetic rats fed with Momordica charantia fruit extract
We studied the long‐term effects of streptozotocin‐induced diabetes on tissue‐specific cytochrome P450 (CYP) and glutathione… 
Highly Cited
1990
Highly Cited
1990
PstI and RsaI RFLPs in complete linkage disequilibrium at the CYP2E gene.
Highly Cited
1988
Highly Cited
1988
Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression.
The human P450IIE1 gene, coding for an ethanol-inducible nitrosamine-metabolizing P-450, was isolated from a lambda EMBL3 genomic… 
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