CYP2E1 wt Allele

Known as: P450C2E, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 wt Allele, CYP2E 
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2018
051019872018

Papers overview

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2004
2004
1: The metabolism by HepG2 cell from two sources (M1, M2) of 12 substrates is reported: ethoxyresorufin, ethoxycoumarin… (More)
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Highly Cited
2003
Highly Cited
2003
Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450… (More)
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2002
2002
PURPOSE This research investigated the biotransformation of thalidomide by cytochrome P-450 (CYP). EXPERIMENTAL DESIGN We used… (More)
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2000
2000
We studied the long-term effects of streptozotocin-induced diabetes on tissue-specific cytochrome P450 (CYP) and glutathione… (More)
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2000
2000
Epoxyeicosatrienoic acids (EETs) are major products of cytochrome P450 (CYP)-catalyzed metabolism of arachidonic acid in the… (More)
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1997
1997
Molecular modelling of substrates of cytochrome P4502E1 (CYP2E1) within the putative active site region of CYP2E1 constructed… (More)
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1995
1995
In primary cultures of human hepatocytes prepared from three separate livers, ethanol increased both CYP3A and CYP2E1, as… (More)
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1994
1994
Tropisetron and ondansetron, which are potent and selective 5-hydroxytryptamine (5-HT3) receptor antagonists, were both… (More)
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1990
1990
Source/Description: A 1.5 kb Apal-Apal fragment, containing 5' upstream sequences of the human CYP2E gene (1). Polymorphism: Pstl… (More)
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1988
1988
The human P450IIE1 gene, coding for an ethanol-inducible nitrosamine-metabolizing P-450, was isolated from a lambda EMBL3 genomic… (More)
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