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CYP2E1 gene
Known as:
CYTOCHROME P450, SUBFAMILY IIE
, Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Gene
, P450C2E
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This gene is involved in the metabolism of both endogenous and exogenous substrates.
National Institutes of Health
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Related topics
Related topics
12 relations
Narrower (1)
CYP2E1 wt Allele
Carcinogen Metabolism
Carcinoma of lung
Cytochrome P-450 CYP2E1
Cytochrome P450 2E1, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Characterization of Cellular Sources and Circulating Levels of Extracellular Vesicles in a Dietary Murine Model of Nonalcoholic Steatohepatitis
Jiahui Li
,
Huimin Liu
,
+8 authors
H. Malhi
Hepatology Communications
2019
Corpus ID: 199069610
Circulating extracellular vesicles (EVs) are a novel and emerging biomarker for nonalcoholic steatohepatitis (NASH). It has been…
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2018
2018
No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population.
Cho-Yin Huang
,
C. Kao
,
C. Chen
,
P. Kuo
,
Ming-Chyi Huang
Journal of the Formosan Medical Association…
2018
Corpus ID: 4377918
2018
2018
Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin
Yankai Wen
,
Chenchen Wang
,
+8 authors
X. Kong
Cellular & Molecular Immunology
2018
Corpus ID: 13690446
Induction of osteopontin (OPN), a well-known pro-inflammatory molecule, has been observed in acetaminophen (APAP)-induced…
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2017
2017
miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 Expression.
Vivek K. Chowdhary
,
K. Teng
,
+11 authors
K. Ghoshal
American Journal of Pathology
2017
Corpus ID: 19347509
2017
2017
Pien Tze Huang Gan Bao attenuates carbon tetrachloride-induced hepatocyte apoptosis in rats, associated with suppression of p53 activation and oxidative stress
Jinyan Zhao
,
Yuchen Zhang
,
Y. Wan
,
Haixia Hu
,
Z. Hong
Molecular Medicine Reports
2017
Corpus ID: 2251478
Pien Tze Huang Gan Bao (PZH-GB), a traditional Chinese medicine, has been used for thousands of years as a protective remedy…
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2017
2017
Does Genetic Loss of Immunoglobulin A Have No Impact on Alcoholic Liver Disease?
Yuan Li
,
W. Ding
Alcoholism: Clinical and Experimental Research
2017
Corpus ID: 29699989
CHRONIC ALCOHOL ABUSE leads to liver injury in the manifestation of hepatic steatosis, hepatitis, fibrosis, cirrhosis, and cancer…
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2011
2011
Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
Daoxiang Zhang
,
T. Xiang
,
Peihan Li
,
Lumin Bao
Genetics and Molecular Biology
2011
Corpus ID: 14598717
The CYP2E1 protein belongs to the P450 enzymes family and plays an important role in the metabolism of small molecular and…
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2004
2004
Use of Molecular Simulation for Mapping Conformational CYP2E1 Epitopes*
M. Vidali
,
M. Hidestrand
,
+6 authors
M. Ingelman-Sundberg
Journal of Biological Chemistry
2004
Corpus ID: 6367625
The identification of the epitopes recognized by autoantibodies against cytochrome P450s (CYPs) associated with drug-induced…
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1995
1995
CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.
K. Iwahashi
,
Y. Matsuo
,
H. Suwaki
,
K. Nakamura
,
Y. Ichikawa
Alcoholism: Clinical and Experimental Research
1995
Corpus ID: 19841005
The genotypes of the CYP2E1 and ALDH2 loci of alcoholic (alcohol dependence) and nonalcoholic (healthy) Japanese were…
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Highly Cited
1995
Highly Cited
1995
Cytochrome P4502E1 genetic polymorphisms and risk of nasopharyngeal carcinoma: results from a case-control study conducted in Taiwan.
A. Hildesheim
,
C. J. Chen
,
+7 authors
C. Yang
Cancer Epidemiology, Biomarkers and Prevention
1995
Corpus ID: 34794225
CYP2E1 is responsible for the metabolic activation of nitrosamines believed to be involved in the pathogenesis of various tumors…
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