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CYP2D6*5 Allele

Known as: CYP2D6 Deleted, CYP2D6*5, CYP2D6D 
Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the entire CYP2D6 gene. Thus… 
National Institutes of Health

Papers overview

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1997
1997
The relationship between therapeutic response to racemic mianserin and steady-state plasma concentrations of S(+)- and R… 
1997
1997
Abstract The relationship between the cytochrome P450 (CYP) 2D6 genotype and the steady-state plasma concentrations (Css) of… 
Highly Cited
1996
Highly Cited
1996
Objective: Debrisoquine hydroxylase (CYP2D6) is responsible for the oxidative metabolism of many clinically used drugs. Since… 
Highly Cited
1996
Highly Cited
1996
The majority of humans deficient in the cytochrome P450 CYP2D6 enzyme, so-called poor metabolizers (PMs), can now be identified… 
Highly Cited
1995
Highly Cited
1995
The CYP2D6 genotype and the debrisoquine and mephenytoin hydroxylation phenotypes were studied in 63 Oriental subjects including… 
1995
1995
1. The pharmacokinetics of ethylmorphine after administration of a single dose of the cough mixture Cosylan were investigated in… 
1994
1994
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR… 
1994
1994
OBJECTIVE To determine whether particular genotypes for the cytochrome P450 enzyme CYP2D6, a polymorphic enzyme, are associated… 
Highly Cited
1993
Highly Cited
1993
The objective of this study was to determine the CYP2D6 genotype of a black Zimbabwean population. Genotyping was carried out… 
Highly Cited
1993
Highly Cited
1993
Polymorphism of the gene encoding for debrisoquine hydroxylase, i.e. CYP2D6, was determined genotypically for 122 healthy…