CYP2D6*5 Allele

Known as: CYP2D6 Deleted, CYP2D6*5, CYP2D6D 
Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the entire CYP2D6 gene. Thus… (More)

Topic mentions per year

Topic mentions per year

1993-2017
0519932017

Papers overview

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2011
2011
AIM To investigate the impact of genetic polymorphisms in CYP2D6, CYP3A5, CYP2C9 and CYP2C19 on the pharmacokinetics of tamoxifen… (More)
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2005
2005
We encountered DNA samples which showed a positive product using a long PCR-based method for the detection of CYP2D6*5… (More)
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2005
2005
BACKGROUND Identification of CYP2D6 alleles *5 (deletion of the whole CYP2D6 gene) and *2xN (gene duplication) is very important… (More)
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2003
2003
AIM To determine the prevalence of most common mutations of cytochrome P450 (CYP), ie, allelic variants of CYP2C9, CYP2C19, and… (More)
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2002
2002
BACKGROUND Cytochrome P450-dependent monooxygenase 2D6 (CYP2D6) activity can be estimated by investigating the metabolism of… (More)
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2001
2001
BACKGROUND Although Malays shared an origin with Chinese, their evolution saw substantial divergences. Phenotyping studies… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Interindividual differences in CYP2D6 activity range from total absence of metabolism of certain drugs to ultrafast… (More)
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2000
2000
AIMS To determine the frequencies of 11 CYP2D6 mutant alleles (CYP2D6*2, *3, *4, *5, *8, *10, *11, *12, *14, *17 and *18), and… (More)
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Highly Cited
1997
Highly Cited
1997
The polymorphic cytochrome P450 2D6 (CYP2D6) causing poor, extensive or ultrarapid metabolism of several clinically important… (More)
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1996
1996
The CYP2D6 gene on human chromosome 22 encodes a cytochrome P450 responsible for oxidative metabolism of over 30 clinically used… (More)
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