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CYP2D6*5 Allele

Known as: CYP2D6 Deleted, CYP2D6*5, CYP2D6D 
Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the entire CYP2D6 gene. Thus… Expand
National Institutes of Health

Papers overview

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1997
1997
The relationship between therapeutic response to racemic mianserin and steady-state plasma concentrations of S(+)- and R… Expand
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1997
1997
Abstract The relationship between the cytochrome P450 (CYP) 2D6 genotype and the steady-state plasma concentrations (Css) of… Expand
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1996
1996
Objective: Debrisoquine hydroxylase (CYP2D6) is responsible for the oxidative metabolism of many clinically used drugs. Since… Expand
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1996
1996
The majority of humans deficient in the cytochrome P450 CYP2D6 enzyme, so-called poor metabolizers (PMs), can now be identified… Expand
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1995
1995
The CYP2D6 genotype and the debrisoquine and mephenytoin hydroxylation phenotypes were studied in 63 Oriental subjects including… Expand
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1995
1995
Recent reports have shown association between CYP2D6 polymorphism and neuronal degenerative diseases such as Parkinson's disease… Expand
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1994
1994
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR… Expand
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1994
1994
OBJECTIVE To determine whether particular genotypes for the cytochrome P450 enzyme CYP2D6, a polymorphic enzyme, are associated… Expand
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1993
1993
The objective of this study was to determine the CYP2D6 genotype of a black Zimbabwean population. Genotyping was carried out… Expand
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1993
1993
Polymorphism of the gene encoding for debrisoquine hydroxylase, i.e. CYP2D6, was determined genotypically for 122 healthy… Expand
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