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CYP1B1 wt Allele

Known as: CP1B, CYPIB1, Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 wt Allele 
Human CYP1B1 wild-type allele is located in the vicinity of 2p22.2 and is approximately 43 kb in length. This allele, which encodes cytochrome P450… 
National Institutes of Health

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Related topics

8 relations
Eye DevelopmentGLAUCOMA 3, PRIMARY CONGENITAL, AIron ChelationMetabolic Detoxication, Drug

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Zinc finger nuclease-mediated knockout of AHR or ARNT in human breast cancer cells abolishes basal and ligand-dependent regulation of CYP1B1 and differentially affects estrogen receptor…
In this study, we used zinc finger nuclease-mediated knockout of the aryl hydrocarbon receptor (AHR) or AHR nuclear translocator… 
2006
2006
Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction.
Benzo[a]pyrene (BP) requires metabolic activation to electrophiles to exert its deleterious effects. We compared the respective… 
2006
2006
Luminescent properties of water-soluble conjugated metallopolymers and their application to fluorescent nitric oxide detection.
Water-soluble pi-conjugated polymers (CPs) incorporating 5,5'-(2,2'-dipyridyl) (CP1) or 6,6'-(2,2'-dipyridyl) (CP2) units within… 
2006
2006
Molecular Analysis of the CYP1B1 Gene: Identification of Novel Truncating Mutations in Patients with Primary Congenital Glaucoma
Background: Mutations and polymorphisms have been identified in the CYP1B1 gene; while mutations that affect the conserved core… 
Highly Cited
2004
Highly Cited
2004
Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis.
Polycyclic aromatic hydrocarbons (PAHs) are known to be activated by the cytochrome P450 (P450) 1 family. However, the precise… 
2004
2004
Cytochrome P4501B1 mutations cause only part of primary congenital glaucoma in Ecuador
Purpose: To determine the role of cytochrome P4501B1 ( CYP1B1 ) mutations in causing primary congenital glaucoma (PCG) in a… 
2003
2003
Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes
Interindividual variation in the expression of the carcinogen‐ and estrogen‐metabolizing enzymes cytochrome P4501B1 and 1A1… 
2000
2000
Cytochrome P 4501 B 1 Mediates Induction of Bone Marrow Cytotoxicity and Preleukemia Cells in Mice Treated with 7 , 12-Dimethylbenz [ a ] anthracene 1
Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) through many environmental pollutants, especially cigarette smoke… 
2000
2000
Prenatal toxicity and lack of carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) following transplacental exposure.
Accumulating evidence from human and experimental animal studies indicates that consumption of heterocyclic amines (HA), derived… 
1999
1999
Evidence for the involvement of the fatty acid and peroxisomal β-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and…
Treatment of intact C3H10T1/2 cells or microsomes therefrom with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benzanthracene… 
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