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CYP11A1 wt Allele

Known as: CYP11A, Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 wt Allele, P450SCC 
Human CYP11A1 wild-type allele is located within 15q23-q24 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 11A1… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Adrenal gonadal, placental and brain mitochondria contain several steroidogenic enzymes, notably the cholesterol side chain… Expand
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Highly Cited
2010
Highly Cited
2010
Steroid hormones regulate diverse physiological functions such as reproduction, blood salt balance, maintenance of secondary… Expand
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Highly Cited
2004
Highly Cited
2004
In adult mammalian brain, occurrence of the synthesis of estradiol from endogenous cholesterol has been doubted because of the… Expand
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Highly Cited
2001
Highly Cited
2001
DAX-1 [dosage-sensitive sex reversal, adrenal hypoplasia congenita (AHC) critical region on the X chromosome, gene 1] is an… Expand
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Highly Cited
2001
Highly Cited
2001
Cytochrome P450scc, the mitochondrial cholesterol side chain cleavage enzyme, is the only enzyme that catalyzes the conversion of… Expand
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Highly Cited
1999
Highly Cited
1999
Polycystic ovary syndrome (PCOS) is a common endocrine disorder of women, characterized by hyperandrogenism and chronic… Expand
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Highly Cited
1998
Highly Cited
1998
Neurosteroids are de novo synthesized in the nervous system through mechanisms at least partly independent of peripheral… Expand
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Highly Cited
1997
Highly Cited
1997
Biochemical data implicate an underlying disorder of androgen biosynthesis and/or metabolism in the aetiology of polycystic ovary… Expand
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Highly Cited
1991
Highly Cited
1991
We have previously demonstrated that tumor necrosis factor alpha (TNF-alpha), a multifunctional cytokine mainly produced by… Expand
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Highly Cited
1987
Highly Cited
1987
P450c17 is the single enzyme mediating both 17 alpha-hydroxylase (steroid 17 alpha-monooxygenase, EC 1.14.99.9) and 17,20 lyase… Expand
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