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CYP11A1 wt Allele

Known as: CYP11A, Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 wt Allele, P450SCC 
Human CYP11A1 wild-type allele is located within 15q23-q24 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 11A1… 
National Institutes of Health

Related topics

Related topics

9 relations
15q23-q24Homo sapiensIron ChelationMetabolic Detoxication, Drug

Broader (1)

CYP11A1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A.
Steroid hormone biosynthesis in the adrenal cortex is controlled by the peptide hormone adrenocorticotropin (ACTH), which acts to… 
Highly Cited
2000
Highly Cited
2000
Organ-specific and non-organ-specific autoantibodies in children and young adults with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
OBJECTIVE The aim of the study was to assess the complex of autoantibodies which can be detected in patients with autoimmune… 
Highly Cited
1994
Highly Cited
1994
Actions of two different cAMP-responsive sequences and an enhancer of the human CYP11A1 (P450scc) gene in adrenal Y1 and placental JEG-3 cells.
Highly Cited
1994
Highly Cited
1994
Transcriptional activation of cytochrome P450 side chain cleavage enzyme expression during trophoblast cell differentiation.
1994
1994
Characterization of adrenal autoantigens recognized by sera from patients with autoimmune polyglandular syndrome (APS) type I.
Steroidogenic enzymes P450scc, P450c17 and P450c21 have recently been shown to be the main autoantigens recognized by sera from… 
Highly Cited
1993
Highly Cited
1993
Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells.
The conversion of cholesterol to pregnenolone, the rate-limiting step in steroid hormone synthesis, occurs on mitochondrial… 
1993
1993
Differential regulation of the CYP11A1 (P450scc) and ferredoxin genes in adrenal and placental cells.
The regulation of the genes encoding cholesterol side-chain cleavage enzyme (P450scc) and ferredoxin, two components in the first… 
1993
1993
Regulation of expression of the CYP11A (P450scc) gene in bovine ovarian luteal cells by forskolin and phorbol esters.
This study examines the transcriptional regulation of the bovine CYP11A (P450scc) gene by activators of protein kinase A and… 
Highly Cited
1991
Highly Cited
1991
Expression of functional bovine cholesterol side chain cleavage cytochrome P450 (P450scc) in Escherichia coli.
Highly Cited
1989
Highly Cited
1989
Interferon-gamma inhibits steroidogenesis and accumulation of mRNA of the steroidogenic enzymes P450scc and P450c17 in cultured porcine Leydig cells.
The inhibitory effects of recombinant porcine interferon-gamma (IFN gamma) on human CG (hCG)-stimulated testosterone production… 
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