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CXADR gene

Known as: COXSACKIEVIRUS B RECEPTOR, COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, CAR 
This gene is involved in both cell-cell adhesion and viral infection.
National Institutes of Health

Related topics

Related topics

7 relations
CLMP protein, humanCell AdhesionCell-Cell Adhesion ProcessCoxsackievirus and Adenovirus Receptor, human

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CXADR wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Cell-Surface Integrins and CAR Are Both Essential for Adenovirus Type 5 Transduction of Canine Cells of Lymphocytic Origin
Adenoviruses are the most widely used vectors in cancer gene therapy. Adenoviruses vectors are well characterized and are easily… 
2017
2017
A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo
To create a new anti-tumor antibody, we conducted signal sequence trap by retrovirus-meditated expression method and identified… 
2016
2016
Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy
Ovarian cancer accounts for >140 000 deaths globally each year. Typically, disease is asymptomatic until an advanced, incurable… 
2012
2012
Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping
Objective: Genetic variants in 296 genes in regions identified through admixture mapping of hypertension, BMI, and lipids were… 
2007
2007
Functional Effects of Coxsackievirus and Adenovirus Receptor Glycosylation on Homophilic Adhesion and Adenoviral Infection
ABSTRACT The coxsackievirus and adenovirus receptor (CAR) is both a viral receptor and homophilic adhesion protein. The… 
2005
2005
Localization of coxsackie virus and adenovirus receptor (CAR) in normal and regenerating human muscle
2003
2003
IGSF11 gene, frequently up-regulated in intestinal-type gastric cancer, encodes adhesion molecule homologous to CXADR, FLJ22415 and ESAM.
EST H04796 is reported frequently up-regulated in intestinal-type gastric cancer based on microarray analysis combined with laser… 
Highly Cited
2002
Highly Cited
2002
Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor.
A replication-defective form of chimpanzee adenovirus type 68 (C68) has been developed to circumvent problems posed by widespread… 
Highly Cited
1999
Highly Cited
1999
CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.
Primary fibroblasts are not efficiently transduced by subgroup C adenovirus (Ad) vectors because they express low levels of the… 
Highly Cited
1999
Highly Cited
1999
Coxsackievirus and Adenovirus Receptor Amino-Terminal Immunoglobulin V-Related Domain Binds Adenovirus Type 2 and Fiber Knob from Adenovirus Type 12
ABSTRACT The extracellular region of the coxsackievirus and adenovirus receptor (CAR) is predicted to consist of two… 
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