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CXADR wt Allele
Known as:
CAR4/6
, HCAR
, CAR
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Human CXADR wild-type allele is located in the vicinity of 21q21.1 and is approximately 81 kb in length. This allele, which encodes coxsackievirus…
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National Institutes of Health
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Related topics
Related topics
7 relations
21q21.1
CLMP protein, human
Cell Adhesion
Cell-Cell Adhesion Process
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Broader (1)
CXADR gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes.
Caitlin Lynch
,
Yongmei Pan
,
+4 authors
Hongbing Wang
Toxicology and Applied Pharmacology
2014
Corpus ID: 24587738
2012
2012
Identification of Novel Activators of Constitutive Androstane Receptor from FDA-Approved Drugs by Integrated Computational and Biological Approaches
Caitlin Lynch
,
Yongmei Pan
,
+4 authors
Hongbing Wang
Pharmaceutical Research
2012
Corpus ID: 17950709
The constitutive androstane receptor (CAR, NR1I3) is a xenobiotic sensor governing the transcription of numerous hepatic genes…
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2011
2011
Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
A. Lau
,
Guixiang Yang
,
Thomas K. H. Chang
Journal of Pharmacology and Experimental…
2011
Corpus ID: 14108084
Naturally occurring splice variants of human constitutive androstane receptor (hCAR) exist, including hCAR-SV23 (insertion of…
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2011
2011
Differential Effect of Meclizine on the Activity of Human Pregnane X Receptor and Constitutive Androstane Receptor
A. Lau
,
Guixiang Yang
,
G. Rajaraman
,
C. Baucom
,
Thomas K. H. Chang
Journal of Pharmacology and Experimental…
2011
Corpus ID: 16806938
Conflicting data exist as to whether meclizine is an activator of human pregnane X receptor (hPXR). Therefore, we conducted a…
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2009
2009
Characterization of the porcine constitutive androstane receptor (CAR) and its splice variants
M. Gray
,
J. Peacock
,
E. Squires
Xenobiotica; the fate of foreign compounds in…
2009
Corpus ID: 10380083
Porcine constitutive androstane receptor (CAR; NR1I3) was cloned and compared for homology and activity with mouse and human CAR…
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2006
2006
Improved gene delivery to B lymphocytes using a modified adenovirus vector targeting CD21.
L. Mailly
,
Laurence Renaut
,
S. Rogée
,
E. Grellier
,
J. D'halluin
,
M. Colin
Molecular Therapy
2006
Corpus ID: 8814044
2005
2005
Retinoid X Receptor-– Dependent Transactivation by a Naturally Occurring Structural Variant of Human Constitutive Androstane Receptor ( NR 1 I 3 )
S. Auerbach
,
M. Stoner
,
S. Su
,
C. Omiecinski
2005
Corpus ID: 35733590
The constitutive androstane receptor (CAR) mediates the hepatic induction of various xenobiotic metabolizing enzymes and…
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2002
2002
Analysis of genetic heterogeneity in the HCAR adenovirus-binding Ig1 domain in a Caucasian Flemish population
I. Thoelen
,
Griet Duson
,
E. Wollants
,
M. Van Ranst
BMC Genetics
2002
Corpus ID: 7096453
BackgroundPolymorphisms in the gene that encodes the human cellular receptor for group B coxsackieviruses and adenoviruses (HCAR…
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2001
2001
Efficient repetitive gene delivery to skeletal muscle using recombinant adenovirus vector containing the Coxsackievirus and adenovirus receptor cDNA
E. Kimura
,
Y. Maeda
,
+6 authors
M. Uchino
Gene Therapy
2001
Corpus ID: 20493940
To improve adenovirus-mediated gene delivery to skeletal muscle, we have used a recombinant adenovirus vector encoding the human…
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1999
1999
Significant increase of adenovirus infectivity in glioma cell lines by extracellular domain of hCAR.
T. Mori
,
H. Arakawa
,
T. Tokino
,
K. Mineura
,
Y. Nakamura
Oncology Research
1999
Corpus ID: 25603431
Recombinant adenoviruses are highly advantageous as vectors for transferring genes into mammalian cells, but the transfer is not…
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