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CRSP3 protein, human

Known as: 130 kDa Transcriptional Co-Activator, Sur2 Mediator subunit protein, human, Sur-2 protein, human 
Mediator of RNA polymerase II transcription subunit 23 (1368 aa, ~156 kDa) is encoded by the human MED23 gene. This protein is involved in the… 
National Institutes of Health

Related topics

Related topics

8 relations
Genes, RegulatorMED23 geneMED23 wt AlleleMediator of activation protein

Broader (1)

Mediator Complex

Papers overview

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Highly Cited
2017
Highly Cited
2017
KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1.
The transcription factor KLF6 has an essential role in the development and metastasis of multiple human cancers. Paradoxically… 
2015
2015
Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex*
Background: Class IIa histone deacetylases (HDACs) repress transcription through association with the SMRT/NCOR co-repressor… 
2015
2015
EVI1 promotes tumor growth via transcriptional repression of MS4A3
BackgroundThe transcription factor Ecotropic Virus Integration site 1 (EVI1) regulates cellular proliferation, differentiation… 
Highly Cited
2010
Highly Cited
2010
Controlling Cellular P-TEFb Activity by the HIV-1 Transcriptional Transactivator Tat
The human immunodeficiency virus 1 (HIV-1) transcriptional transactivator (Tat) is essential for synthesis of full-length… 
Highly Cited
2005
Highly Cited
2005
In Vitro Analysis of Huntingtin-Mediated Transcriptional Repression Reveals Multiple Transcription Factor Targets
2005
2005
PI3-kinase and PDK-1 regulate HDAC1-mediated transcriptional repression of transcription factor NF-kappaB.
PDK-1 activates PI3-kinase/Akt signaling and regulates fundamental cellular functions, such as growth and survival. NF-kB is… 
Highly Cited
2003
Highly Cited
2003
Role of Metazoan Mediator Proteins in Interferon-Responsive Transcription
ABSTRACT The interferon (IFN)-induced signal transduction and transcription activation complex, ISGF3, is assembled from three… 
Highly Cited
2002
Highly Cited
2002
A new cellular factor recognizes E2 binding sites of papillomaviruses which mediate transcriptional repression by E2.
Repression of transcription by the full-length E2 protein of papillomaviruses (PV) seems to occur when the E2 binding sites and… 
Highly Cited
1997
Highly Cited
1997
Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenes
Transcription of the human papillomavirus type 18 (HPV18) E6 and E7 oncogenes is repressed by the viral E2 protein. In C33 cells… 
Highly Cited
1995
Highly Cited
1995
Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.
The S/G2‐specific transcription of the human cdc25C gene is due to the periodic occupation of a repressor element (‘cell cycle… 
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